Clinical Research Directory

A candidate will be eligible if they meet all the following criteria: * Age 18-80 years at time of enrollment. * Diagnosis of moderate to extreme binge eating disorder (BED) per DSM-5-TR criteria * Participant is able and willing to give informed consent. * Participant is willing to cooperate with the study requirements, including compliance with the regimen, completion of all study visits, and study assessments. * Participants of reproductive potential must have negative pregnancy test and agree to use acceptable forms of contraception. * Participant able to communicate sensations during the procedure. A candidate will be excluded if they meet any of the following criteria: * Unable to undergo MR-imaging or clinically significant MRI findings * History of any clinically significant neurological disorder. * Evidence of substance (alcohol or other drug) use disorder during the previous 12 months . * Past or present diagnosis of psychotic disorder or bipolar disorder * Currently taking opioid pain medications or positive drug screen for opiates. * If participants are on medication for the treatment of binge eating disorder or obesity (they must be on a stable dose for at least one month and agree to not begin a medication until after their Week 12 visit. * Subject has a lifetime history or current symptoms consistent with bulimia nervosa or anorexia nervosa . * Have a recorded or self-reported change in body weight \>11 lbs. within 3 months prior to screening * Have a prior or planned surgical treatment for obesity (excluding lap-band if removed \>6 months prior to screening or liposuction or abdominoplasty if performed \>1 year prior to screening) * Have or plan to have endoscopic and/or device-based therapy for obesity or have had device removal within the last 6 months prior to screening * History of medically verified suicide attempt within the past year. Clinically significant suicide risk * Participant who is currently participating in another clinical investigation with an active treatment arm. * Participant is considered to be a poor surgical or study candidate, which may include, but is not limited to the following: any medical, social, or psychological problem that could complicate the required procedures and evaluations of the study in the judgment of the investigator. * Participant is pregnant/ lactating or planning to be pregnant.