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NOT YET RECRUITING
NCT07908654
PHASE3

A Study to Evaluate Efficacy, Immunogenicity and Safety of a Recombinant Respiratory Syncytial Virus Vaccine in Older Adults Aged 60 Years and Older

Sponsor: Guangzhou Patronus Biotech Co., Ltd.

View on ClinicalTrials.gov

Summary

This is a randomized, observer-blinded, placebo-controlled Phase III clinical trial to evaluate efficacy, immunogenicity and safety of the Respiratory Syncytial Virus (RSV) Vaccine, LYB005 in participants aged 60 years and older.

Official title: A Randomized, Observer-blind, Placebo-controlled Phase III Clinical Trial to Evaluate the Efficacy, Immunogenicity, and Safety of the Respiratory Syncytial Virus (RSV) Vaccine, LYB005 in Older Adults Aged 60 Years and Older

Key Details

Gender

All

Age Range

60 Years - Any

Study Type

INTERVENTIONAL

Enrollment

25000

Start Date

2026-11

Completion Date

2027-12

Last Updated

2026-11-03

Healthy Volunteers

Yes

Interventions

BIOLOGICAL

LYB005

0.5 mL per dose.

BIOLOGICAL

Placebo

0.5 mL 0.9% sodium chloride (normal saline) injection per dose

Locations (1)

Jiangsu Provincial Center for Disease Control and Prevention (Jiangsu Provincial Academy of Preventive Medicine)

Nanjing, Jiangsu, China