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NOT YET RECRUITING
NCT07909915
PHASE4

Effectiveness and Tolerability of a Treat-to-Target Versus Fixed-Dose Statin Strategy in Patients With Atherosclerotic Cardiovascular Disease: A Randomized Controlled Trial

Sponsor: Rehman Medical Institute - RMI

View on ClinicalTrials.gov

Summary

To compare the efficacy of fixed-dose versus treat-to-target statin regimens in achieving the predefined LDL-C target at 12 weeks in patients with established ASCVD. To compare the frequency of adverse effects of statin therapy between patients receiving a fixed-dose regimen and those managed with a treat-to-target approach.

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

178

Start Date

2026-11

Completion Date

2027-06

Last Updated

2026-11-02

Healthy Volunteers

No

Interventions

DRUG

Dose adjustment of statins

dose will be titrated as per patient's LDL on follow-up. It is not routinely done

DRUG

no dose adjustment

no drug dose adjustment will be done in this group

Locations (1)

Rehman Medical Institute

Peshawar, KPK, Pakistan