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Effectiveness and Tolerability of a Treat-to-Target Versus Fixed-Dose Statin Strategy in Patients With Atherosclerotic Cardiovascular Disease: A Randomized Controlled Trial
Sponsor: Rehman Medical Institute - RMI
Summary
To compare the efficacy of fixed-dose versus treat-to-target statin regimens in achieving the predefined LDL-C target at 12 weeks in patients with established ASCVD. To compare the frequency of adverse effects of statin therapy between patients receiving a fixed-dose regimen and those managed with a treat-to-target approach.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
178
Start Date
2026-11
Completion Date
2027-06
Last Updated
2026-11-02
Healthy Volunteers
No
Conditions
Interventions
Dose adjustment of statins
dose will be titrated as per patient's LDL on follow-up. It is not routinely done
no dose adjustment
no drug dose adjustment will be done in this group
Locations (1)
Rehman Medical Institute
Peshawar, KPK, Pakistan