Clinical Research Directory

Inclusion Criteria: 1. ≥18 years of age 2. Capable and willing to give informed consent 3. Candidate for an elective, non-emergent catheter-based procedure via the common femoral vein 4. Eligible and planned same day discharge 5. Able and willing to complete Patient Experience questionnaire and standard of care follow-up (2 week automated phone call and 30-Day +/- 14 days follow-up in-person or telemed visit). Exclusion Criteria: 1. Currently involved in any other investigational clinical trial that may interfere with the outcomes of this study, in the opinion of the Investigator 2. Pre-existing immunodeficiency disorder and/or chronic use of high dose systemic steroids 3. Known history of bleeding diathesis, bleeding problems following medical procedures, or coagulopathy 4. Known baseline hemoglobin \< 10 g/dl, hematocrit \< 30%, platelet count \< 100,000 cells/mm3 5. Severe co-existing morbidities, with a life expectancy of less than 12 months in the opinion of the Investigator 6. Known history of deep vein thrombosis or pulmonary embolism in the last 12 months 7. Known allergy/adverse reaction to bovine derivatives 8. Active systemic infection, or cutaneous infection or inflammation in the vicinity of the groin 9. Unable to ambulate at least 20 ft at baseline 10. Pregnant (known or suspected) or lactating 11. Extreme morbid obesity (BMI greater than 45 kg/m2) or underweight (BMI less than 20 kg/m2) 12. Known planned procedures or known concomitant condition(s) that may extend ambulation attempts beyond 2-4 hours, and/or hospitalization time (e.g., staged procedure, serious co-morbidity), in the opinion of the Investigator 13. Femoral vessel closure in either limb with any of the following conditions: 1. Planned femoral access in the next 60 days to reflect the device re-access period 2. Any residual hematoma, significant bruising, or known associated vascular complications 3. Use of an intra-vascular closure device within the previous 90 days 4. Access within \< 10 days 14. Currently known implanted vascular grafts/stents at the access site that would interfere with the planned closure procedure, in the opinion of the Investigator \-