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Effect of Oxybutynin on Opioid Use After Urologic Surgery in Children
Sponsor: University of Calgary
Summary
The goal of this clinical trial is to determine whether giving oxybutynin before urologic reconstruction surgery reduces the amount of opioid pain medication needed in children. Oxybutynin is a medication that helps reduce bladder spasms, which can cause pain and discomfort after surgery. The main question this study aims to answer is: Does giving oxybutynin before surgery reduce the amount of opioid pain medication children need during the first 6 hours after surgery? Researchers will compare oxybutynin with a placebo (a tablet containing no active medication) to see whether oxybutynin reduces opioid use after surgery.
Official title: A Randomized Double-Blind Placebo-Controlled Trial Evaluating the Opioid-Sparing Effect of Preoperative Oxybutynin in Children Undergoing Urologic Reconstruction
Key Details
Gender
All
Age Range
Any - 17 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2026-11-01
Completion Date
2028-11-01
Last Updated
2026-11-02
Healthy Volunteers
No
Interventions
Oxybutynin
Participants will receive oxybutynin 0.2 mg/kg (to a maximum dose of 5 mg), orally administered by the day surgery nurse in the day surgery holding area prior to surgery.
Placebo
Participants will receive a matching placebo tablet, orally administered by the day surgery nurse in the day surgery holding area prior to surgery.
Locations (1)
Alberta Children's Hospital
Calgary, Alberta, Canada