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LacriFill Canalicular Occlusion for Dry Eye After LASIK
Sponsor: Mann Eye Institute
Summary
This study is a single-site, prospective, randomized (2:1) controlled study of subjects aged 18-39 who are candidates for bilateral LASIK and have dry eye symptoms (OSDI ≥13). The LacriFill group (n=50) receives bilateral lower canalicular LacriFill placement within 7 days prior to surgery plus standard postoperative care; the control group (n=25) receives standard postoperative care only. The primary outcome is the change in Ocular Surface Disease Index (OSDI) score from baseline to 3 months after bilateral LASIK.
Official title: Impact of LacriFill Lacrimal Occlusion on Post-LASIK Dry Eye Symptoms, Ocular Surface Recovery, and Patient-Reported Visual Quality
Key Details
Gender
All
Age Range
18 Years - 39 Years
Study Type
INTERVENTIONAL
Enrollment
75
Start Date
2026-12-09
Completion Date
2027-12-31
Last Updated
2026-11-03
Healthy Volunteers
No
Conditions
Interventions
LacriFill Canalicular Filler
LacriFill, a crosslinked hyaluronic acid-based bioresorbable gel, instilled for bilateral lower canalicular occlusion within 7 days prior to LASIK surgery.
Locations (1)
Mann Eye Institute
Houston, Texas, United States