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Sex Differences in BDNF Study
Sponsor: McMaster University
Summary
A single bout of exercise can improve cognitive abilities like memory and attention. These functions help us navigate through everyday life. However, we do not fully understand how exercise improves cognitive abilities. We believe that exercise improves the brain by increasing the amount of BDNF in the blood. BDNF is very important for learning and memory. However, we still do not know if BDNF responds differently to exercise between females and males. The purpose of this work is to characterize potential sex-differences in the circulating BDNF response to acute exercise. We will test the hypothesis that males will have greater serum and plasma BDNF responses compared to females following a maximal exercise test.
Official title: Investigation of Sex-differences the BDNF Response to Exercise
Key Details
Gender
All
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2026-11
Completion Date
2027-02
Last Updated
2026-11-03
Healthy Volunteers
Yes
Conditions
Interventions
VO2peak Test
Incremental ramp test to volitional exhaustion on a cycle ergometer.
Locations (1)
McMaster University
Hamilton, Ontario, Canada