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Diaphragm Ultrasound and Neuromuscular Monitoring for Predicting Early Respiratory Events After Extubation
Sponsor: Mustafa Duran
Summary
The goal of this prospective observational study is to learn whether diaphragm ultrasound and quantitative neuromuscular monitoring can predict early respiratory events after extubation in adults having elective surgery under general anesthesia. The main questions it aims to answer are: * Are lower diaphragm thickening fraction and diaphragm excursion before extubation associated with early respiratory events after extubation? * How well do diaphragm ultrasound parameters and the train-of-four (TOF) ratio predict these events? Participants will receive their usual anesthesia care. Diaphragm ultrasound will be performed at four time points: before induction of anesthesia, 5 minutes after induction, before extubation, and 30 minutes after extubation in the post-anesthesia care unit (PACU). The TOF ratio will be recorded with routine quantitative neuromuscular monitoring. Respiratory events will be recorded from extubation until discharge from the PACU.
Official title: Evaluation of the Relationship Between Diaphragm Ultrasonography, Neuromuscular Monitoring Parameters and Extubation Success in Patients Undergoing Elective Surgery: A Prospective Observational Study
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2026-11-01
Completion Date
2027-01-10
Last Updated
2026-11-03
Healthy Volunteers
No
Conditions
Interventions
Diaphragm ultrasonography4
Right hemidiaphragm ultrasonography in the supine position. Diaphragm thickness at end-inspiration and end-expiration is measured with a linear probe at the zone of apposition, and diaphragm thickening fraction is calculated. Diaphragm excursion is measured with M-mode. Each parameter is measured three times at four time points: before induction, 5 minutes after induction, before extubation, and 30 minutes after extubation in the PACU.