Clinical Research Directory

Inclusion Criteria: * Adult females aged 18 to 70 years. * Able to provide written informed consent. * Clinical indication for two endosseous dental implants at clinically comparable sites in the same participant. * Edentulous sites (healed or not fully healed) with sufficient bone volume. Minor bone augmentation is permitted only if identical at both paired sites. * Comparable paired sites regarding jaw, region, and planned implant diameter and length. The same implant dimensions must be used at both sites. * Bone density corresponding to D2 or D3 (350-1250 HU); dense D1 sites are excluded. * Good oral hygiene and periodontal stability. * Adequate inter-arch space and mouth opening for fully guided surgery. Exclusion Criteria: * Uncontrolled systemic disease. * Pregnancy or lactation. * Previous high-dose radiotherapy to the jaws or current chemotherapy. * Current intravenous antiresorptive therapy (e.g., bisphosphonates). * Heavy smoking (\> 10 cigarettes/day) or substance abuse. * Severe parafunctional habits. * Active infection or untreated periodontitis at the planned sites. * Sites requiring different grafting procedures between the two sides. * D1 dense cortical bone or inability to perform the CCW protocol. * Inability to obtain two comparable eligible sites.