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COMPLETED
NCT07913633
NA

Comparison Of Ultrasound Guided Transversus Abdominis Plane Block Versus Wound Infiltration With Local Anesthetics for Post Operative Analgesia

Sponsor: Mayo Hospital Lahore

View on ClinicalTrials.gov

Summary

This randomized controlled trial compared two methods of pain relief after inguinal hernia repair: an ultrasound-guided transversus abdominis plane (TAP) block and local anesthetic injection around the surgical wound. The study tested the hypothesis that average pain scores differed between the two methods. The study was conducted in the Department of Anesthesia at King Edward Medical University/an affiliated hospital in Lahore. Eighty male patients aged 18-60 years who underwent planned inguinal hernia repair were included. Patients were randomly assigned by a lottery method to two groups of 40 patients each. One group received an ultrasound-guided TAP block, in which bupivacaine, a local anesthetic, was injected into a space between the abdominal muscle layers to numb the nerves supplying the surgical area. The other group received the same dose of bupivacaine injected into and around the wound margins. Both groups also received paracetamol and diclofenac for pain relief. The main outcome was the average pain score four hours after treatment. Pain was assessed using a visual analogue scale ranging from 0 to 10, where 0 represented no pain and 10 represented the worst pain. Further pain assessments continued for up to 24 hours after surgery, and patients were monitored for complications related to either procedure.

Official title: Comparison Of Ultrasound Guided Transversus Abdominis Plane Block Versus Wound Infiltration With Local Anesthetics for Post Operative Analgesia After Inguinal Hernia Repair

Key Details

Gender

MALE

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2026-01-01

Completion Date

2026-06-30

Last Updated

2026-11-03

Healthy Volunteers

No

Interventions

PROCEDURE

Ultrasound-Guided Transversus Abdominis Plane Block

Under ultrasound guidance, a 25-gauge spinal needle was advanced using an in-plane approach into the plane between the internal oblique and transversus abdominis muscles. Bupivacaine was injected after identification of the target plane, and its spread was confirmed by ultrasound.

PROCEDURE

Local Anesthetic Wound Infiltration

The surgeon injected bupivacaine into and around the surgical wound margins using a 20-mL syringe and a 25-gauge needle.

DRUG

Bupivacaine

Bupivacaine, 0.5%, 1.5 mg/kg, administered into the transversus abdominis plane.

Locations (1)

Mayo Hospital, Lahore

Lahore, Punjab Province, Pakistan