Clinical Research Directory

Inclusion Criteria: * The inclusion criteria comprised medically healthy patients with clinical findings consistent with pulpal necrosis, with or without an associated periapical lesion, and radiographic evidence of incomplete root development, defined by an apical diameter \>1 mm Exclusion Criteria: * Teeth were excluded if they exhibited a vital pulp and/or complete root maturation, were non-restorable, demonstrated radiographic evidence of root fracture, or if the patient had allergy to any medication or material required for the treatment protocol. Teeth associated with periodontal probing depths \>4 mm were also excluded