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The Mepilex Cesarean Delivery Trial / MEPIDEL
Sponsor: Montefiore Medical Center
Summary
The goal of this clinical trial is to learn whether a silver-containing foam dressing (Mepilex Border Post-Op Ag) works as well as the standard dressing in preventing surgical site infection after cesarean delivery. The main questions it aims to answer are: Is the rate of surgical site infection with Mepilex Border Post-Op Ag no worse than with the standard dressing? How do the two dressings compare for other wound problems, wound-related hospital or clinic visits, and patient satisfaction? Researchers will compare participants who receive Mepilex Border Post-Op Ag with participants who receive the standard dressing. Participants will: 1. Have their cesarean delivery as planned by their care team 2. Be randomly assigned to one of the two dressings, which is placed over the incision at the end of surgery 3. Complete a short questionnaire about their dressing 4. Receive a follow-up phone call about 30 to 40 days after delivery (POD 30-40) to check on their wound
Official title: A Randomized Controlled Non-Inferiority Trial of Mepilex Border Post-Op Ag Versus Standard Postoperative Dressing Following Cesarean Delivery
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
240
Start Date
2026-11
Completion Date
2027-11
Last Updated
2026-11-03
Healthy Volunteers
Yes
Conditions
Interventions
Mepilex Border Post-Op Ag
An FDA-cleared (510(k) K100029), self-adherent, silver-containing soft silicone foam dressing (Mölnlycke Health Care) indicated for postoperative wounds. Applied according to manufacturer labeling.
Standard Postoperative Dressing
A sterile Telfa non-adherent pad (Cardinal Health) covered with sterile gauze and secured with a Primapore adhesive dressing (Smith \& Nephew). This is the institution's routine postoperative cesarean dressing.
Locations (1)
Montefiore-Einstein Jack D. Weiler Hospital
The Bronx, New York, United States