Clinical Research Directory

Advance Care Planning Impact on the Consistency of Older Adults With Lung Cancer and Their Potential Surrogates Regarding Life-Sustaining Treatment Preferences

This randomized controlled trial examined whether an advance care planning (ACP) tabletop game ("Walking with Wishes") could improve the consistency of life-sustaining treatment preferences between older adults with lung cancer and their potential surrogates (family members or friends), compared to a standard ACP manual. Eligible dyads (patient-surrogate pairs) were randomized 1:1 to either the tabletop game intervention or the ACP manual control group. The primary outcome was the absolute gap score on the modified Life Support Preferences Questionnaire (m-LSPQ), measuring the difference between patient and surrogate preferences for five life-sustaining treatments (antibiotics, CPR, surgery, nasogastric tube feeding, and intravenous infusion) across nine health scenarios. Secondary outcomes included state anxiety (STAI-S) for both patients and surrogates. The m-LSPQ was assessed at baseline (T0), 2 weeks (T2), and 6 weeks (T3) post-intervention. The STAI-S was additionally assessed immediately post-intervention (T1) to capture acute emotional responses to the intervention.

Platform for End-of-life Awareness, Conversations, and Education (PEACE) Among Registered Nurses

The goal of this clinical trial is to evaluate whether the PEACE program can improve early career registered nurses' registered nurses' attitudes towards caring for palliative patients, ability to cope with patients' death, and self-efficacy in initiating advanced care planning conversations This study aims to address the following research questions: * Does the PEACE program improve early career registered nurses' attitudes towards caring for palliative patients, ability to cope with patients' death and self-efficacy in initiating advanced care planning conversations? * What are the participants' experiences of participating in the PEACE program? Researchers will compare participants who receive the PEACE program (death conversation and online ACP education) with participants who receive only the online ACP education to see if informal death conversations improve early career registered nurses' attitudes towards caring for palliative patients, ability to cope with patients' death and self-efficacy in initiating advanced care planning conversations. Participants will: * Complete online questionnaires measuring attitudes towards caring for palliative patients, ability to cope with patients' death and self-efficacy in initiating advanced care planning conversations. * Participate in a facilitator-led group discussion session about experiences of patients' deaths, coping with patients' death and dying, communications with patients and/or family members about death and dying, and discussing advance care planning with patients and/or family members (intervention group only). * Complete an asynchronous online ACP education session consisting of short recorded videos and an online discussion forum (both intervention and control group). * Complete follow-up surveys, including a 3-month follow-up assessing whether participants have engage with any patients and/or their family members in advance care planning conversations.

Die-logue Program for Community Dwelling Adults: A Randomized Controlled Trial

The goal of this clinical trial is to evaluate whether the Die-logue program can improve attitudes toward death, coping with death, and readiness for advance care planning (ACP) among community-dwelling middle-aged adults aged 40-60 years who have not completed any advance directives and not diagnosed with any life limiting diseases. This study aims to address the following research questions: * Does the Die-logue program improve community-dwelling middle-aged adults' attitudes towards death, ability to cope with death, readiness and uptake for Advanced Care Planning (ACP). * What are community-dwelling middle-aged adults' perceptions of advance care planning, death and dying, and their experiences of participation in the Die-logue program. Researchers will compare participants who receive the Die-logue program (death conversation and online ACP education) with participants who receive only the online ACP education to see if informal death conversations improve attitudes toward death, coping with death, and readiness for ACP. Participants will: * Complete online questionnaires measuring attitudes toward death, coping with death, and readiness for advance care planning. * Participate in a facilitator-led group discussion session about perceptions of death, coping with death, and readiness for ACP (intervention group only). * Complete an asynchronous online ACP education session consisting of short recorded videos and an online discussion forum (both intervention and control group). * Complete follow-up surveys, including a 6-month follow-up assessing whether they have undertaken advance care planning.