Clinical Research Directory

Circadian-informed Optimal Bedtime

The goal of this interventional study is to test whether circadian-informed bedtime recommendations can improve sleep, next-day psychomotor vigilance, and subjective well-being among healthy adults. The main questions it aims to answer are: * Can Optimal Bedtime derived from data collected by a consumer smartwatch increase the objective total sleep time? * Can Optimal Bedtime derived from data collected by a consumer smartwatch reduce the count of lapse in a next-day Psychomotor Vigilance Task? * Can Optimal Bedtime derived from data collected by a consumer smartwatch increase subjective sleep quality? Researchers will compare Optimal Bedtime with a placebo bedtime and an unguided baseline in a cross-over design. Participants will: * Be randomized 1:1 to either Optimal Bedtime then placebo or placebo then Optimal Bedtime. * Wear a consumer smartwatch for 6 weeks, 2 weeks in each of baseline, Optimal Bedtime, and placebo. * Complete a Psychomotor Vigilance Task and a subjective well-being survey every morning.

Fatigue in Long-Haul Operations

The purpose of the present study is to test novel countermeasures to reduce fatigue among airline pilots during long-haul flight operations. The investigators will collect objective and subjective sleep, sleepiness, workload, and performance data from active-duty line pilots flying long-haul flight operations (\>8 hours). Data will be collected during days off prior to the trip start, during flights and layover, and during days off following the trip end.