Clinical Research Directory

SmartEnLite for Nursing Home Residents With Dementia

The goal of this clinical trial is to learn if the Smart Environmental Lighting (SmartEnLite) can help improve behaviors and sleep among residents with dementia in nursing homes. The main questions it aims to answer are: * What is the effect of SmartEnLite on mood and behaviors? * What is the effect of SmartEnLite on sleep? * Would the effect of SmartEnLite on sleep affect its effect on mood and behaviors? Researchers will compare the SmartEnLite to the usual light in nursing homes to see if the SmartEnLite works to improve behaviors and sleep in nursing home residents with dementia. Participants will: * Participate in the study for 13 weeks with SmartEnLite for 4 weeks and their usual light. * Wear a sensor for 13 weeks to measure their sleep and light exposure. * Be observed for mood, behaviors, and reactions to the lights every other week.

Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome

The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function, dual task standing and walking, and other metrics of mobility in older adults with motoric cognitive risk syndrome (MCR).

Designing Care Management for Hospice Transitions for Persons Living With Advanced Dementia

This study will test a care management intervention to guide end-of-life care and hospice transitions for persons with dementia and their care partners receiving home healthcare and ascertain feasibility, acceptability, fidelity, and usability of a dementia care management hospice transitions checklist. This study will also examine hospice enrollment, time to enrollment, and care partner satisfaction with the intervention. The intervention will be delivered within usual care management within a large home healthcare agency.

Aligning Medications With What Matters Most

The Aligning Medications with What Matters Most (ALIGN) study will assess the feasibility and preliminary efficacy of a deprescribing intervention to reduce medication regimen complexity and treatment burden for people living with dementia (PLWD) and their care partners.

Promoting Positive Care Interactions (PPCI) in Assisted Living

The overall aim of this study is to pilot test Promoting Positive Care Interactions (PPCI) with the goal of establishing a feasible and culturally responsive approach to optimize care interactions between staff (nursing, activity, housekeeping, and dining service staff) and residents with ADRD in assisted living facilities (ALFs), and further improve select resident, staff, and facility outcomes. PPCI is a non- pharmacological four-step approach consisting of (1) stakeholder engagement in developing facility specific goals; (2) environment and policy assessments; (3) flexible staff education; and (4) ongoing mentorship, motivation, and support (in-person visits and text messages) for staff to optimize care interactions.