Clinical Research Directory

The Effectiveness of Bowel Preparation in Colonoscopy Patients Using Artificial Intelligence-assisted Nursing Education

Background: Colonoscopy is a critical diagnostic and screening tool for colorectal cancer, and its effectiveness largely depends on bowel preparation quality. Traditionally, bowel preparation education has been provided by nurses using written materials and verbal instructions. However, clinical workload pressures and staffing shortages frequently result in inadequate patient comprehension and poor adherence, negatively impacting bowel cleanliness, polyp or adenoma detection rates, examination quality, and overall medical efficiency. Recent advancements in artificial intelligence (AI) suggest potential improvements in patient education and adherence through AI-based interventions. Nevertheless, systematic studies assessing the effectiveness of AI smartphone applications (APPs) specifically tailored for bowel preparation education within local cultural and clinical contexts remain limited. Objective: This study aims to evaluate the effectiveness of an AI-integrated smartphone application designed for bowel preparation education before colonoscopy, focusing on patient cognition regarding bowel preparation, satisfaction with nursing education, and bowel cleanliness outcomes. Methods: A randomized controlled trial was conducted in the gastroenterology ward of a regional hospital in southern Taiwan. A total of 140 hospitalized patients scheduled for colonoscopy were enrolled and randomly assigned to either the experimental group (n=70) or the control group (n=70). The experimental group received multimodal education through an AI-based smartphone application, featuring visual and textual information, educational videos, and interactive chatbot dialogues. In contrast, the control group received conventional written and verbal nursing instructions. Demographic data were collected prior to colonoscopy. Post-examination evaluations included bowel cleanliness assessment (using the Aronchick Scale), nursing education satisfaction, and bowel preparation cognition questionnaires administered before and after the intervention. The overall effectiveness of the APP-based intervention was analyzed. Keywords: Artificial Intelligence, Bowel Preparation, Colonoscopy, Smartphone Application

Administration of a 'Thirst Relieve Kit' Versus Placebo in Patients After Hospital-based Bowel Preparation for Colonoscopy and Assessment of Thirst Intensity

The goal of this study is to evaluate whether a "thirst kit" (lemon popsicle) is effective in reducing thirst intensity in patients undergoing hospital bowel preparation for colonoscopy. The study also aims to assess the impact of the thirst kit on associated symptoms and patient satisfaction. The main questions it aims to answer are: * Does the thirst kit reduce the intensity of thirst after bowel preparation for colonoscopy? * Does the thirst kit reduce symptoms such as dry mouth and dry throat? * How satisfied are patients when using the thirst kit compared to a placebo? Researchers will compare the thirst kit to a placebo to determine its effectiveness in managing thirst during the pre-colonoscopy period. Participants will: * Be randomly assigned to receive either the thirst kit (lemon popsicle) or a placebo * Use the assigned intervention during the hospital preparation period for colonoscopy * Rate thirst intensity, associated symptoms, and satisfaction using numerical scales

Individualized Non-pharmacological Intervention for Bowel Preparation

Colonoscopy is essential for the early detection of colorectal cancer. However, inadequate bowel preparation remains a common challenge, associated with reduced adenoma detection rates, prolonged procedure time, and increased healthcare costs. Current individualized regimens rely largely on higher laxative dosages-an approach with limited clinical utility. Non-pharmacological interventions, including dietary modification, physical activity, and health education, are safe and tend to have better patient adherence. The effectiveness of health education depends largely on message framing. Guided by information-framing theory, we developed an individualized non-pharmacological regimen. This randomized controlled trial aims to evaluate the efficacy of this regimen in improving bowel preparation quality.

Assessment of Safety, Quality, and Acceptance of a Bowel Preparation Using a Food Kit With Laxatives

The main purpose of this research study is to learn if an alternative bowel preparation (bowel prep) for colonoscopy is safe, tolerable and effective as compared to the standard bowel prep. Participants are randomly assigned to receive one of the following bowel cleansing regimens for colonoscopy. * Standard Bowel Prep which includes a clear liquid diet the day before the scheduled procedure and two doses of a laxative, polyethylene glycol 3350 (PEG-3350) taken with 4 liters of water. * Happy Colon Foods Bowel Prep which begins the day before the scheduled procedure and contains various low residue foods (foods that are easily digested and absorbed), and seven doses of laxatives including PEG-3350 taken with a total of about 4 liters of water, senna tablets, and one dose of magnesium citrate.

Intestinal Preparation in Colonoscopy: Lactulose vs Sodium Phosphate.

To compare intestinal preparation with Lactulose vs. Sodium Phosphate as the better agent for performing high-quality colonoscopies at the Civil Hospital Fray Antonio Alcalde and the Civil Hospital Juan I. Menchaca, both in Guadalajara, Mexico; as well as Hospital Santo Tomás in Panama City, Panama; and Hospital Gustavo Nelson Collado Ríos in Chitré, Panama; during the period from April 1, 2025, to November 30, 2025. The comparison will focus on colonoscopy quality, patient tolerance, satisfaction, and electrolyte changes, using the agents orally as part of the bowel preparation prior to the colonoscopy procedure.

Exploring the Clinical Value of an AI-Assisted Patient Self-Assessment App for Bowel Preparation: A Multicenter Study

The quality of bowel preparation hinges on how well patients follow the prep-drug regimen, so intensive education is essential. Phone calls, texts, short videos, and mini-programs have all been shown to boost compliance and improve prep quality. Still, we also need a way to spot-early-those patients who are likely to prep poorly so we can step in with a rescue plan. In our pilot work the investigators built an AI-assisted mini-program that lets patients photograph their effluent and get an instant quality read-out. The single-center RCT showed excellent performance. Because these findings came from one center, the investigators are now launching a multicenter study to test the tool more broadly. Patients will use the AI mini-program at home; if the algorithm predicts inadequate prep it will prompt them to come in early or alert staff so the investigators can initiate a rescue protocol and, ultimately, improve bowel-cleansing quality.

The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality

The goal of this clinical trial is to learn how GLP-1 and GIP agonists effect bowel preparation in patients scheduled for colonoscopies. The main questions it aims to answer are: * Does GLP-1 and GIP agonist increase the rate of inadequate bowel preparation? * Does the quality of bowel preparation differ in patients who hold vs. those who continue a single dose of their GLP-1 or GIP agonist medication? * Are there any differences in the rates of complications gastric aspiration in patients who hold vs. continue a single dose of their GLP-1 or GIP agonist medication?

Efficacy, Safety and Tolerability of Magnesium Sulfate With Low-volume Polyethylene Glycol for Colonoscopy Cleansing

Magnesium salts such as magnesium citrate are often combined with polyethylene glycol to make the intestinal preparation before colonoscopy, which has shown high cleaning efficacy. Magnesium sulfate combined with polyethylene glycol is less used in the world. This multicenter, randomized, controlled trial is aimed at to evaluate the efficacy and safety of magnesium sulfate combined with low-volume polyethylene glycol for preoperative bowel preparation for colonoscopy.

A Study to Investigate the Effect of a Meal At 6pm the Day Before the Colonoscopy on the Bowel Cleansing with Plenvu

Bowel cleansing prior to colonoscopy is crucial to be able to perform a high-quality examination. Therefore maximum efforts are made to achieve optimal bowel cleansing including diet restriction and refraining from day-before dinner. However, the effect of this interdiction is currently not clear. On the other hand, patient compliance and experience with the entire procedure is important, especially for follow-up colonoscopies. Strict diets may interfere with this as an additional burden on the patient. In this study we want to assess whether a more lenient diet influences the quality of bowel preparation and whether it improves patient's experience.