Clinical Research Directory

Immediate Effects of Postural Restoration Exercises and Breathing on Shoulder and Pelvic Mobility

Prolonged sedentary behavior and habitual poor posture often lead to asymmetrical muscular loading and restricted joint mobility, such as glenohumeral internal rotation deficit (GIRD). Traditional interventions primarily focus on passive, localized stretching. However, the human body functions as an interconnected kinetic chain, where the mobility of distal joints (like the shoulder) is heavily influenced by the axial alignment of the thorax and pelvis, as well as breathing mechanics. This study aims to investigate the immediate effects of Postural Restoration Exercises (PRE)-which uniquely combine specific asymmetrical positioning with prolonged exhalation techniques-on pelvic alignment and shoulder mobility in healthy young adults. Using a dismantling design, participants are assigned to three groups: the Postural Restoration Exercise (PRE) group, the Positional Exercise (PE) group, and the Breathing Exercise (BE) group. By comparing these groups, the study seeks to isolate and clarify whether the restorative benefits stem primarily from limb positioning, breathing mechanics, or the integration of both. The ultimate goal is to provide evidence for a highly efficient, self-administered intervention to improve motor performance and reduce injury risk.

Investingation on Outcomes After Combining Septoplasty With Additional Procedures.

The aim of this study will be to compare postoperative nasal airflow and symptom improvement using a NOSE form in patients after different types of surgical treatment. Patients will be treated with one of the following operations: septoplasty with turbinectomy, septoplasty with radiofrequent ablation of the nasal turbinates, or septoplasty with valvuloplasty. This is a single-center prospective randomized interventional comparative study on patients in a tertiary rhinology center, who will undergo septoplasty alongside one additional rhinologic procedure aimed at improving nasal patency.

Ventilator Mode and Respiratory Physiology

Modern intensive care units (ICUs) are increasingly adopting newer modes of mechanical ventilation such as adaptive pressure control (APC) modes but there are limited data available regarding risks and benefits of newer modes versus traditional ventilation modes. APC can inadvertently deliver high tidal volumes, which maybe harmful. High tidal volumes may be unrecognized by the provider, due to the complexities of ventilator algorithms and patient interactions. The objective of this aim is to identify risk factors for excess tidal volumes in patients on adaptive pressure control.