Clinical Research Directory

Digital Use, 24-Hour Movement Behaviors, and Myofascial Release in University Students With Neck Pain

This study will examine how smartphone use recorded by the phone and daily sleep, sitting, and physical activity are related to neck posture, sensitivity to pressure, and body awareness in university students aged 18 to 30 years. One hundred students will complete seven days of smartphone and activity monitoring and clinical assessments. Among these students, 56 who have nonspecific neck pain for at least three months, average pain of at least 3 out of 10, and forward head posture will be randomly assigned to integrated myofascial release or a light-touch control. Both groups will receive six sessions over two weeks. An assessor who does not know the assigned group will measure outcomes before and after treatment and, where feasible, one month after treatment. The study will investigate whether myofascial release improves neck pain, pressure pain threshold, posture, movement, disability, and awareness.

Gyrokinesis for Chronic Nonspecific Neck Pain

The Gyrokinesis is a mind-body exercise that activates the entire body through spinal articulations and undulating rhythms integrated with specific breathing patterns. This study will determine the effects of GK versus conventional therapeutic exercises on the Numeric Pain Rating Scale (NPRS), cervical range of motion (ROM), deep neck flexor control ability, Neck Disability Index Scores, proprioceptive repositioning ability, and Fear-Avoidance Beliefs. There will be two groups: experimental and control. Half of the study group will receive training with Gyrokinesis, and the other half will receive training with conventional therapeutic exercises.

Comparative Effectiveness Randomised Controlled Trial of Hybrid Muscle Conditioning

Chronic nonspecific neck pain is a prevalent and recurrent condition frequently characterised by persistent impairments in cervical-scapular neuromuscular function. Deep cervical flexor motor-control deficits and reduced upper trapezius endurance represent two clinically relevant but distinct manifestations of neuromuscular dysfunction. Deep cervical flexor motor-control exercise targets cervical segmental control and movement coordination, while upper trapezius endurance exercise targets at the mechanical capacity of the cervical-scapular system. Although both exercise approaches have demonstrated clinical benefit when used independently, it remains unknown whether combining these two exercises as compared to single-exercise approach would provide additional or synergistic effects on the clinical recovery for individuals with chronic nonspecific neck pain. This three-arm comparative randomised controlled trial will investigate a 5-week hybrid programme combining deep cervical flexor motor-control and upper trapezius endurance exercise as compared to their single-exercise comparator programme (i.e., deep cervical flexor motor-control exercise alone or upper trapezius endurance exercise alone) in managing the clinical recovery of adults with chronic nonspecific neck pain. Two hundred and ten participants will be randomly allocated to one of the three groups (70 participants per group) upon the completion of the baseline evaluation of the study outcomes. All programmes will use standardised exercise procedures, individualised progression, supervised instruction, and structured home exercise format. Study outcomes will be assessed at baseline, immediately after the 5-week intervention, and 6 months after programme completion in order to enable the evaluation of the exercise programme effectiveness at immediate and longer-term. The primary objective is to determine the effectiveness of hybrid exercise programme as compared to the two single-component exercise programmes on the primary outcomes namely neck pain intensity, neck-related disability and upper-extremity physical function, and general health status (as secondary outcome) at immediate (change between pre- and post-programme of the 5-week programme) and longer-term reassessments (change between pre-programme and 6-month after the 5-week programme). The secondary objective aims to study the mechanisms underpinning the observed effectiveness produced by the exercise programmes by evaluating the changes in neuromuscular and muscle-mechanical function, including deep cervical flexor performance, upper trapezius endurance, joint position error, muscle mechanical properties and vascularity, together with changes in pain sensitivity, exercise-induced hypoalgesia, and pain-related and exercise-specific self-efficacy, at both the immediate and longer-term reassessments. Findings this trial will provide evidence if differential effectiveness on clinical outcomes present when rehabilitating adults with chronic nonspecific neck pain using combined and single-component exercise approaches. Furthermore, findings of the mechanism-mediation analysis will provide a scientific basis for more targeted, mechanism-informed exercise prescription for chronic nonspecific neck pain. Overall, results to be obtained from this trial will help refine the therapeutic exercise prescription and promote the outcome recovery for conservative management of this highly prevalent spinal condition.

Effects of Diaphragmatic Breathing Exercises on Pain, Grip Strength, and Anthropometric Measures in Women With Chronic Nonspecific Neck Pain

Chronic nonspecific neck pain may affect the mechanical loading of the cervical region and trunk stabilization. Diaphragmatic breathing exercises may contribute to postural control and trunk stabilization in addition to their role in breathing. This randomized controlled study investigated the effects of adding diaphragmatic breathing exercises to posture and core stabilization exercises on pain, grip strength, and anthropometric measurements in women with chronic nonspecific neck pain. Forty women aged 18-60 years with chronic nonspecific neck pain lasting at least three months participated in the study. Participants were randomly assigned to an intervention group or a control group, with 20 participants in each group. Both groups performed posture and core stabilization exercises twice weekly for eight weeks. The intervention group additionally performed 10 minutes of diaphragmatic breathing exercises during each session. Pain intensity, right and left hand grip strength, body mass index, waist-to-hip ratio, and waist-to-height ratio were assessed before and after the exercise program. Pain was assessed using the Visual Analog Scale, grip strength using a hydraulic hand dynamometer, and anthropometric measurements according to International Society for the Advancement of Kinanthropometry standards. The results showed that adding diaphragmatic breathing exercises may provide additional benefits, particularly in reducing activity-related pain in women with chronic nonspecific neck pain.