Clinical Research Directory

Early Versus Delayed Ileostomy Closure Following Bowel Surgery

Temporary ileostomy is commonly created following bowel surgery to protect distal anastomoses and reduce the consequences of anastomotic leakage. However, the optimal timing for ileostomy closure remains controversial. Early closure may improve quality of life and reduce stoma-related complications, whereas delayed closure may allow better recovery but prolong stoma-related morbidity and hospital care. This randomized controlled trial aims to compare the mean post-operative hospital stay between early (within 8 weeks) and delayed (after 8 weeks) ileostomy closure following bowel surgery. Sixty eligible patients will be randomized equally into two groups. The findings will help determine the optimal timing of ileostomy reversal and may improve patient outcomes while reducing healthcare utilization.

Operating-Room Distractions, Surgeon Workload, Anxiety, Teamwork and Intraoperative Adverse Events (ORCHESTRA)

During surgery, telephone calls, conversations, equipment problems and other events may distract the operating team. Some events interrupt the progress of the operation. The surgeon's workload and anxiety, together with how well the team works together, may also be related to events that occur during surgery. ORCHESTRA is an observational study of patients undergoing colorectal or anal surgery in a single hospital. Trained observers record distractions during routine operations. After each operation, the surgeon reports workload and anxiety, and an observer assesses teamwork. Intraoperative adverse events are graded using a standard severity classification. The study examines how these measurements are related. It does not assign treatments, introduce distractions or change routine surgical care.

Effect of Oral Laxative Use Before Colorectal Surgery on Intraoperative Surgical Difficulty

This prospective randomized pilot study will evaluate whether the use of an oral laxative before elective laparoscopic colorectal surgery affects small-bowel diameter and intraoperative surgical difficulty. Adult patients scheduled for elective laparoscopic colorectal resection will be randomly assigned to receive either oral laxative plus rectal enema preparation or rectal enema preparation alone. During surgery, the diameters of the jejunum and ileum will be measured using a standardized method. The study will also compare operative difficulty, bowel manipulation time, operation duration, need for additional ports, conversion to open surgery, intraoperative complications, blood loss, and early postoperative outcomes between the two groups. The findings may help clarify whether oral laxative use influences intraoperative conditions during laparoscopic colorectal surgery.