Clinical Research Directory
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4 clinical studies listed.
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Tundra lists 4 Dark Spots clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT07900217
A Clinical Study to Assess the Effects of a Dark Spot Corrector on Dark Spots and Overall Complexion
This is a single-group, open-label, 90-day clinical study to assess the effectiveness of the Dark Spot Corrector by DIME Beauty on reducing the visibility of dark spots and improving overall complexion in females aged 50-65. Thirty-five participants will apply 2 pumps of the product to their entire face twice daily (morning and night) after cleansing and toning. Efficacy will be evaluated through subject-specific self-reported questionnaires administered at Baseline, Day 14, Day 30, Day 60, and Day 90, as well as expert skin grading and before-and-after photographs taken at Baseline, Day 30, Day 60, and Day 90. The study will also assess secondary outcomes including changes in skin brightness, smoothness, radiance, and evenness of complexion.
Gender: All
Ages: 50 Years - 65 Years
Updated: 2026-10-28
1 state
NCT07477275
Combination of Oral and Topical Whitening Agents for Reducing Skin Pigmentation
The goal of this study is to evaluate the safety and efficacy of a combination use of oral supplement and topical serum in improving skin pigmentation in healthy women. The main questions it aims to answer are: Does combination use able to reduce the dark spot? Is there any adverse effect associate with the product use?
Gender: FEMALE
Ages: 30 Years - 60 Years
Updated: 2026-07-31
1 state
NCT07644871
A 4-week Study Investigating Two Targeted Brightening Serum (A and B) Versus 4% Hydroquinone in Women With Mild to Severe Full-face Hyperpigmentation
This a short four-week pilot study to measure the efficacy and tolerance of two brightening serums (cosmetics) versus 4% hydroquinone. The study was conducted in two sites across the USA, one in PA and in one in CA. The goal was to run the pilot study in the summer to understand the role of these two potential brightening serums in helping the appearance of skin tone evenness.
Gender: FEMALE
Ages: 20 Years - 60 Years
Updated: 2026-06-12
1 state
NCT07324759
Clinical Study to Assess Safety, Effectiveness and In-Use Tolerability of Saffron Extract Capsules for Improving Skin Health and Reducing Signs of Aging on Healthy Adult Male and Female Subjects.
This is a randomized, double-blind, comparative, two-arm, prospective, interventional, multi-centre clinical study to evaluate the safety, efficacy, and in-use tolerability of test products, standardized saffron extract capsules, on skin rejuvenation and age-defying benefits in healthy adult male and female subjects.
Gender: All
Ages: 30 Years - 55 Years
Updated: 2026-01-07