Clinical Research Directory
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3 clinical studies listed.
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Tundra lists 3 Dose Finding Study clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT07894484
Lactium Premedication to Prevent Emergence Agitation
This biased coin sequential allocation, dose finding study will be conducted to determine the effective dose of oral lactium in 90% of children (ED90) for prevention of emergence agitation during recovery from adenotonsillectomy.
Gender: All
Ages: 3 Years - 12 Years
Updated: 2026-10-27
1 state
NCT04730609
Dexmedetomidine for Intraoperative Shivering in Scheduled Elective Cesarean Delivery
The purpose of this study is to determine the optimum dose of Dexmedetomidine to stop shivering in 90% of patients who experience shivering during scheduled elective cesarean deliveries.
Gender: FEMALE
Ages: 18 Years - Any
Updated: 2026-09-18
1 state
NCT07374952
Minimal Effective Volume 90% for Double-injection Costoclavicular Block
In 2020, a trial demonstrated that a 2-injection technique constitutes the optimal method for the costoclavicular block. This study aims to determine the minimum amount of medication required to achieve a successful double-injection costoclavicular nerve. Block dose assignment will be done using an up-and-down sequential method, called the Biased Coin Design (BCD). The double-injection technique for US-guided costoclavicular block consists in depositing two thirds of the LA volume in the deep compartment (to anesthetize the posterior and medial cords), and one third of the injectate in the superficial compartment (to anesthetize the lateral cord). The ED90 will be calculated using isotonic regression with a 95% confidence interval derived by bootstrapping.
Gender: All
Ages: 18 Years - 70 Years
Updated: 2026-07-07
1 state