Clinical Research Directory

Effects of Hydrogen-rich Water Consumption on Transient Fatigue During an Official Football Match.

The purpose of this study is to determine whether drinking hydrogen-rich water can reduce fatigue and help football players maintain high-intensity physical activity during an official football match. The study will include 30 male football players competing in the second and third tiers of the Czech national football league system. Participants will be randomly assigned to drink either hydrogen-rich water or placebo water. Neither the players nor the researchers conducting the assessments will know which type of water each participant receives until the study has been completed. Participants will begin drinking the assigned water 72 hours before the match and will continue drinking it on match day. Players' physical activity and heart rate will be monitored throughout the match. The main outcome will be the distance covered at high intensity during consecutive 5-minute periods of the match. Repeated-sprint ability, jumping performance, and perceived muscle soreness will also be assessed before and after the match. The study will compare the hydrogen-rich water and placebo groups to determine whether hydrogen-rich water helps players maintain high-intensity activity during the match and reduces short-term fatigue after the match.

Muscle Oxygenation and Autonomic Recovery After Repeated Sprint in Competitive Soccer Players

This study evaluates the acute and short-term recovery responses to repeated sprint exercise in competitive male soccer players. Forty-eight licensed male soccer players complete an 8 × 30 m repeated sprint protocol under field conditions, with 25 seconds of active recovery between sprints. The study examines several aspects of recovery. Muscle oxygenation is assessed using portable near-infrared spectroscopy sensors placed on the vastus lateralis and biceps femoris muscles. Cardiac autonomic recovery is evaluated using heart rate variability measurements obtained at baseline, 5 minutes, 30 minutes, and 24 hours after the repeated sprint protocol. Countermovement jump performance is measured before the protocol, 10 minutes after the protocol, and 24 hours later. Sprint performance, blood lactate concentration, and perceived exertion are also recorded to characterize the physiological and performance demands of the repeated sprint protocol. The study aims to determine how muscle oxygenation, cardiac autonomic recovery, and neuromuscular performance change during the recovery period following repeated sprint exercise and whether these recovery indicators are associated with repeated sprint performance.

The Effect of Individual Sodium Citrate Consumption on Repeated Sprint Performance in Female Soccer Players

The aim of this research is to determine whether sodium citrate supplementation, taken at the best individual time, would improve repeated sprint performance in professional female soccer players. The main questions it aims to answer are: 1. Does sodium citrate improve sprint times, peak power, minimum power, and mean power during repeated sprints? 2. Does sodium citrate lower fatigue index (the drop in power across sprints) during repeated sprint exercise? 3. Does sodium citrate change blood bicarbonate, pH, and lactate levels before and after exercise? 4. Does sodium citrate affect how hard exercise feels (perceived exertion)?

Whole-Body Cryotherapy and Isokinetic Performance After Exercise-Induced Fatigue

This randomized crossover study investigated the effects of whole-body cryotherapy (WBC) on isokinetic knee performance following running-induced fatigue in physically active healthy male university students. Participants completed two recovery conditions, WBC and passive rest, on separate days following a standardized treadmill fatigue protocol. Knee extension and flexion strength were assessed using an isokinetic dynamometer at angular velocities of 60°/s and 240°/s. In addition, blood pressure, heart rate, oxygen saturation, and perceived fatigue responses were monitored throughout the recovery period. The study aimed to determine whether WBC improves post-exercise recovery and lower-extremity muscle performance compared with passive rest.