Clinical Research Directory

Mineral-Infused Clothing for Recovery From Muscle Soreness and Muscle Damage After Exercise

The goal of this clinical trial is to learn whether wearing mineral-infused clothing helps muscles recover after a hard bout of unaccustomed exercise in healthy adults aged 18 to 45 who have not done lower-body resistance or jump training in the last 6 months. The main question it aims to answer is: does wearing the mineral-infused garment lead to greater recovery of leg muscle strength (maximal voluntary isometric contraction of the knee extensors) 72 hours after exercise, compared with wearing an identical garment without the mineral infusion? Researchers will also compare the two garments for recovery of jump performance, muscle soreness and blood creatine kinase (a marker of muscle damage), and will describe garment comfort and tolerability. Participants will: * Complete electronic consent, an online screening questionnaire and a video screening call * Attend the study site on four consecutive days * On Day 1, complete baseline tests, then perform 100 drop jumps (5 sets of 20) to cause muscle soreness * Wear their allocated garment for at least 16 hours a day (day and overnight) for the following 72 hours and keep a daily wear log * Have strength, jump and soreness tests and a finger-prick blood sample at each visit (24, 48 and 72 hours after exercise)

Curcumin Versus Ibuprofen for Exercise-Induced Muscle Damage in Physically Active Women

xercise-induced muscle damage (EIMD) is a common consequence of unaccustomed or high-intensity exercise and is characterized by muscle soreness, impaired physical performance, inflammation, oxidative stress, and increased circulating biomarkers of muscle damage. Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are frequently used to alleviate these symptoms, although their repeated use may be associated with adverse effects. Curcumin, a natural polyphenol with antioxidant and anti-inflammatory properties, has emerged as a potential nutritional strategy to support post-exercise recovery. This randomized, double-blind, placebo-controlled trial aims to compare the effects of oral curcumin supplementation and ibuprofen administration on exercise-induced muscle damage in physically active women. The study evaluates clinical outcomes, physical performance, biomarkers of muscle damage, inflammation, oxidative stress, and other health-related biomarkers to determine whether curcumin may represent a safe and effective nutritional alternative for promoting recovery after eccentric exercise.

A Clinical Trial to Evaluate the Effects of Peptide Gummies on Markers of Inflammation, Physical Performance, and Recovery

This study will evaluate the effects of Parlay Recover peptide gummies (containing Body Protection Compound BPC-157) on markers of inflammation, physical performance, and recovery in physically active adults. Over an 8-week period, 40 participants will consume two gummies daily and complete questionnaires at Baseline, Week 2, Week 4, Week 6, and Week 8, as well as undergo blood testing at Baseline and Week 8. The primary objective is to examine changes in inflammatory biomarkers (hs-CRP and IL-6) as measured by blood testing. Secondary objectives include evaluating participants' self-reported perceptions of the product's effects on physical performance and recovery, including aching, stiffness, function, and recovery of muscles and joints.