Clinical Research Directory

EVS With Exercise for Balance With Older Adults

This study will test whether electrical stimulation of the balance system adds benefit to an exercise program for adults aged 60 years and older. The treatment is called noisy electrical vestibular stimulation (nEVS). It uses low-level electrical current delivered through electrodes placed behind the ears and on the neck. Participants who join the trial will be assigned by chance, in equal numbers, to active nEVS or sham nEVS. Sham sessions use the same equipment and preparation and will have no current delivered. Both groups will attend the RISE STRONG exercise program for 12 weeks. Exercise classes take place twice weekly and last about 35 to 45 minutes. Participants will attend 18 active or sham sessions over six weeks. Each session lasts 20 minutes. Two sessions each week may take place on exercise days, and one additional weekly visit is expected. The stimulation course may take place during exercise weeks 1 to 6 or 7 to 12. Standing balance will be measured before and after the six-week course to compare the two groups. Other assessments examine walking, physical function, cognition, and self-reported health. The study will also record attendance, treatment completion, and adverse events.

Effects of Unilateral Versus Bilateral Task Specific Training With Visual Feedback in Post Stroke Patients

This study will be a single blinded randomized controlled trail. Non probability convenience sampling will be used to recruit the patients of either gender, aged 40-65 years, patients with the subacute phase (\>3months post stroke) and able to follow the instructions. This study will be carried out in Gulab Devi Hospital and Sahet Medical Complex Lahore. These participants will be randomly allocated to Group A will receive bilateral task specific training with visual feedback, whereas Group B will receive unilateral task specific training with visual feedback. Both group will perform their respective exercises 40 minutes, five days a week for 6weeks. The Participants will be evaluated at the start and end of the exercise program through Berg Balance scale to assess balance, 10 Meter Walk Test to assess gait and Fugl Meyer Assessment of lower extremity to assess sensation. Data will be analyzed by SPSS version 27.

Tele-Supervised Dual-Task Balance Training in Community-Dwelling Older Adults at Risk of Falls

Dual-task training combines movement with cognitive tasks to improve gait, balance, and thinking. This study will compare tele-supervised versus onsite dual-task balance training in older adults at risk of falls. Sixty participants aged 65+ will be randomly assigned to either remote or face-to-face training for 8 weeks. Both groups will follow the same program, delivered via video calls or direct supervision. Outcomes measures will include gait speed, balance, and cognition using the 10-Meter Walk Test (10MWT), Berg Balance Scale (BBS), and Trail Making Test Part B (TMT-B).

Health and Gait Outcomes in Elderly Dancers Compared to Inactive Adults

The aim of this observational study is to assess functional fitness and spatial-temporal gait parameters in individuals aged 65 years and over who regularly participate in senior dance classes. These outcomes will be compared with those of two inactive control groups: aged-matched older adults and inactive middle-aged individuals (aged 25-40 years) who have not engaged in any structured physical activity in the past six months. Furthermore, our study aimed to assess the correlation between the duration of participation in senior dance and the measured variables including physical fitness, gait characteristics, and mental well-being.

The Effect of Balance-focused Exercise Programme in Enhancing the Solus-muscle Activation During Gait Initiation for People With Parkinson Disease

Gait initiation (GI) is a crucial component of walking that requires a balanced muscle activity and postural stability. GI could be challenging for people with neurological condition such as people with Parkinson (PWP), where GI is usually impaired. The purpose of this study is determining effectiveness of comprehensive, balanced-focused exercise programme in controlling the activation of Solus-muscle in people with Parkinson disease. We hypothesise that balance-focus exercise programe could improve Solus-muscle activation during GI. study type: this is a parallel group prospective (10 weeks) randomised single-blinded controlled trial conduct in Kuwait. Participant: People with Parkinson, who met the inclusion criteria.

Effects of Motor Imagery Training

Parkinson's disease (PD) is the second most common neurodegenerative disease, characterized pathologically by the progressive loss of dopaminergic neurons in the substantia nigra and clinically by the presence of motor symptoms such as bradykinesia, resting tremor, and/or rigidity. Among the motor deficits frequently observed in PD, patients are known to frequently report difficulties with manual dexterity.Typical features of balance deficits in PD include decreased sway, decreased base of support, rigidity, abnormal intersegmental coordination, and postural misalignment. Related somatosensory deficits in PD include problems orienting to and processing sensory and somatosensory information.Motor imagery (MI) is the imaginal execution of motor activities or the activation of specific muscles in the absence of any explicit feedback. This area of rehabilitation has been shown to be effective in improving and developing motor skills in many neurological conditions where patients exhibit motor recognition and execution impairments. MI can be applied at all stages of recovery from PD, is highly effective in movement-related pathologies, and can be performed independently.Studies evaluating the effect of mental imagery training on balance measures in PD are limited. One study evaluating the effect of combined MI-physical therapy versus physical therapy alone group treatment noted positive trends toward balance improvements in the combined group. In a case study of a single participant with PD, a 3-month neurocognitive rehabilitation program incorporating mental imagery over 20 sessions resulted in balance improvements and a reduced risk of falls in both the "OFF" and "ON" phases, as measured by the Tinetti Balance and Gait Assessment Scale.The aim of this study is to investigate the effects of motor imagery training on kinesiophobia, walking and balance in patients with Parkinson's disease.