Clinical Research Directory

Effects of Supervised Aerobic Exercise on Biomarkers in Patients With nSCLC Receiving Immunotherapy

Exercise is increasingly recognized as a supportive intervention in oncology and may influence systemic inflammation, immune regulation, physical function, and the tumor microenvironment among patients with non-small cell lung cancer. The EXIMPACT trial will investigate the effects of a supervised aerobic exercise program on immune system- and tumor microenvironment-related biomarkers in patients with NSCLC receiving active immunotherapy. Although immunotherapy has improved outcomes for patients with NSCLC, factors influencing treatment response and strategies to enhance treatment efficacy remain under investigation.

Acute Effects of Saccadic Eye-Movement Exercise on Flexibility and Handgrip Strength

This randomized controlled trial investigated whether a short session of saccadic eye-movement exercises could produce immediate changes in flexibility and handgrip strength in healthy adults. Thirty participants were randomly assigned to either an experimental group or a control group. The experimental group completed a standardized four-phase eye-movement exercise protocol lasting approximately 6-8 minutes, while the control group rested quietly for the same period. Firat\_Caglar\_Frontiers\_Eda Flexibility was assessed using the sit-and-reach test, and maximal handgrip strength was measured for both hands before and immediately after the intervention. The study aimed to determine whether brief saccadic eye-movement exercise could acutely influence these physical performance measures compared with resting. Firat\_Caglar\_Frontiers\_Eda The study was conducted in healthy adults in a single-session design. All 30 participants completed the study, and no adverse events such as dizziness, nausea, nystagmus, or visual discomfort were reported.

High-protein Oral Nutrition With HMB for Active CD Patients With Sarcopenia

The efficacy of B-hydroxy-β-methybutyrate in sarcopenia