Clinical Research Directory

A Patient Navigation Trial for Housing and Health (PATHH)

This study will describe and evaluate the experiences and outcomes of women who have survived violence and also have medical needs. The intervention we are testing is a service called 'PATHH', a patient navigation service that extends after a stay in an emergency shelter. Some people who join the study will work with the PATHH patient navigator, and some will receive standard care at the community shelter. Participants who are assigned the PATHH navigator will receive additional support and help linking with services in the community during and after their emergency shelter stay. By doing this study, we hope to learn how patient navigation services affect the health and housing stability among women who have survived violence.

Comprehensive Enhanced Care Management Under CalAIM for High-Risk Medi-Cal Members

This pragmatic, cluster-randomized trial will evaluate whether a comprehensive CalAIM-aligned care model consisting of Enhanced Care Management, selected Community Supports, Transitional Care Services, and residential care coordination improves population health outcomes among high-risk Medi-Cal managed care members in California compared with usual CalAIM service delivery. The intervention is intended to improve continuity of care after discharge, reduce potentially avoidable utilization, increase successful linkage to outpatient and social supports, and improve community tenure and patient-reported outcomes.

Transitional Housing and HIV Health

The goal of this pilot study is to evaluate the implementation and outcomes of the Arms Around You (AAY) program, a supportive housing initiative launched by the Philadelphia Department of Public Health (PDPH) in 2024. The program aims to address housing instability among people with HIV (PWH) using a Housing First model. The main questions it seeks to answer are: 1. How does AAY affect HIV-related outcomes, particularly viral suppression and antiretroviral therapy (ART) adherence? 2. What are the program's effects on economic, psychological, and secondary health outcomes? 3. How feasible, acceptable, and scalable is the program for broader implementation? Participants will be assigned to immediate program access or a waitlist using a random lottery system, creating treatment and control groups, respectively. Surveys and health data will be collected at baseline and over 36 months to assess changes in outcomes such as viral suppression, housing security, mental health, and financial well-being. Qualitative interviews with participants and stakeholders will complement quantitative findings to explore mechanisms of change and guide program optimization.