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Clinical Research Directory

Browse clinical research sites, groups, and studies.

3 clinical studies listed.

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Immune Responses

Tundra lists 3 Immune Responses clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ACTIVE NOT RECRUITING

NCT07870954

Comparative Study Between the Effects of Deep Versus Moderate Neuromuscular Blockade on Postoperative Recovery and Immune Function in Patients Undergoing Total Hip Replacement Surgery.

. The investigators hypothesized that DNMB ( Deep NeuroMuscular Block) would yield superior postoperative recovery quality and attenuate the surgery-induced immune suppression compared to MNMB ( Moderate NeuroMuscular Block)in patients undergoing THA (Total Hip Arthroplasty).

Gender: All

Ages: 16 Years - 60 Years

Updated: 2026-10-13

Immune Responses
Post Operative Recovery
RECRUITING

NCT07779265

Effects of Probiotic Supplementation on Gut Health, Immune Response, and Well-Being

This randomized, double-blind, placebo-controlled exploratory study will evaluate the effects of daily probiotic supplementation on gut barrier function, immune-related markers, and well-being in healthy adults with mild to moderate perceived stress. 50 participants will be randomly assigned to receive either a probiotic supplement or placebo for 8 weeks. Blood and stool samples will be collected before and after the intervention to assess markers of gut barrier function, intestinal inflammation, gut microbiome composition, short-chain fatty acids, and immune function. Participants will also complete questionnaires on stress, quality of life, mood, digestive symptoms, and bowel habits. Safety will be evaluated throughout the study by monitoring adverse events and vital sign assessments.

Gender: All

Ages: 18 Years - 65 Years

Updated: 2026-08-21

Gut Microbiome
Immune Responses
Well-being
ACTIVE NOT RECRUITING

NCT06079606

The Effects of Antibiotic Exposure in Early Infancy on Vaccine Responses

This prospective cohort study will include 200 term children born in Landspitali University Hospital in Iceland. The cohort will be divided into four groups according to antibiotic exposure of which one is the control group. Children's immune responses to live oral rotavirus vaccine as well as conventional vaccinations given at three, five and 12 months old will be determined by measuring salivary and serologic responses. Responses will be compared between the four groups. Stool samples will also be collected from participants and the composition of the microbiome compared between the four groups.

Gender: All

Ages: Any - 6 Weeks

Updated: 2025-12-18

Immune Responses
Antibiotic Treatment