Clinical Research Directory
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Tundra lists 2 Locally Advanced Resectable Rectal Cancer clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT07905950
Exploratory Study of Short-Course Radiotherapy Followed by Adebrelimab Combined With Chemotherapy for Organ Preservation in Locally Advanced Rectal Cancer
This prospective, single-arm, exploratory clinical study aims to evaluate the efficacy and safety of short-course radiotherapy (SCRT) sequentially followed by adebrelimab combined with chemotherapy as an organ-preservation strategy in patients with locally advanced resectable rectal cancer. Approximately 155 eligible patients will be enrolled after providing full written informed consent and passing screening, and will receive SCRT followed by adebrelimab plus chemotherapy. The primary efficacy endpoint is the complete response (CR) rate assessed at the end of Cycle 4 or Cycle 8 of treatment. Efficacy evaluation will be conducted after 4 cycles of treatment, and subsequent treatment regimens will be determined according to each patient's condition.
Gender: All
Ages: 18 Years - 75 Years
Updated: 2026-10-30
1 state
NCT07454720
A Clinical Study of Adebrelimab in Combination With SHR-8068 and Chemoradiotherapy as Perioperative Therapy for Locally Advanced Rectal Cancer
The study is being conducted to evaluate the safety and efficacy of Adebrelimab and SHR-8068 in combination with chemoradiotherapy in subjects with rectal cancer.
Gender: All
Ages: 18 Years - 75 Years
Updated: 2026-05-05
2 states