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Locally Resectable Pediatrics Tumors

Tundra lists 1 Locally Resectable Pediatrics Tumors clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ACTIVE NOT RECRUITING

NCT06986811

CEB-01 in Pediatrics With Locally Resectable Abdominal Tumors

The CEB-01 implant is a membrane containing SN-38, the active metabolite of irinotecan, an already authorized chemotherapeutic agent. After surgical removal of the abdominal cancer tumor, CEB-01 will be placed in the surgical bed for a local and sustained release of the chemotherapy. This is expected to delay or prevent local recurrence of abdominal tumors after surgery, while keeping a tolerable toxicity profile. The study aims to assess the safety, tolerability, pharmacokinetics, and efficacy of CEB-01 in pediatric patients with locally resectable abdominal tumors including Soft Tissue Sarcoma (STS), high-risk Neuroblastoma (NB), Wilms tumor (WT), germ cell tumors (GCT), extracranial malignant rhabdoid tumor (eMRT), synovial sarcoma (SS), desmoplastic small round cell tumor (DSRCT) and fibrolamellar hepatocellular carcinoma (FL-HCC)

Gender: All

Ages: Any - 18 Years

Updated: 2026-10-20

1 state

Locally Resectable Pediatrics Tumors