Clinical Research Directory

Does Injection Target Matter in Sacroiliac Joint Dysfunction?

This retrospective comparative cohort study aims to compare the short-term clinical outcomes of ultrasound-guided sacroiliac joint (SIJ) injection, combined SIJ and multifidus injection, and multifidus injection alone in patients with sacroiliac joint dysfunction. Medical records of patients who underwent ultrasound-guided injection procedures were retrospectively reviewed and classified into three groups according to the documented injection target: SIJ injection alone, combined SIJ and multifidus injection, and multifidus injection alone. The primary outcome is the change in pain intensity during movement, assessed using the Visual Analog Scale (VAS) from baseline to 30 minutes after injection. Pain outcomes at one week and changes in functional measures, including the Roland-Morris Disability Questionnaire and Oswestry Disability Index, are evaluated as secondary outcomes. The study aims to determine whether short-term pain and functional outcomes differ according to the injection target.

Effects of Isolated Lumbar Extension Resistance Training Alone and in Combination with General Exercise and Manual Therapy

This study examines effects of machine-based isolated lumbar extension resistance exercise (ILEX) on paraspinal muscle morphology and function, as well as pain intensity, disability and quality of life in patients with chronic low back pain and radiculopathy related to specific spinal disorders. Current guidelines emphasize the necessity of treating chronic low back pain with integrative, holistic approaches due to its multidimensional nature. At the same time, an increasing number of studies highlight the importance of restoring lumbar muscle function and morphology through targeted training. Regarding ILEX, existing studies already support its clinical value, however, the optimal integration of ILEX with other therapeutic modalities remains unclear. Two groups will be enrolled in an ILEX protocol (16 weeks, 25 sessions), while one of the groups will additionally participate in general exercise and manual therapy. After completion of the main program, participants will be given different options to continue the exercise therapy with a reduced frequency (e.g., once per month). After six months, a follow-up assessment will be conducted with all participants to analyze long-term efficacy.