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Clinical Research Directory

Browse clinical research sites, groups, and studies.

4 clinical studies listed.

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Non-radiographic Axial Spondyloarthritis

Tundra lists 4 Non-radiographic Axial Spondyloarthritis clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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COMPLETED

NCT05155098

2 Years Prospective Study to Collect Real-life Data on the Retention, Quality of Life, Effectiveness and Treatment Pattern of Secukinumab in Adult Patients With Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis, Ankylosing Spondylitis and Non-radiographic Axial Spondyloarthritis

This was an observational, prospective primary data collection study. The duration of observation was 2 years after study enrolment date. Disease and treatment history were retrospectively reviewed from medical record at enrollment with no time limits for the key diagnosis of enrolment (plaque psoriasis, psoriatic arthritis, ankylosing spondylitis and non-radiographic axial spondyloarthropathy).

Gender: All

Ages: 18 Years - 80 Years

Updated: 2026-10-23

3 states

Moderate to Severe Plaque Psoriasis
Psoriatic Arthritis
Ankylosing Spondylitis
+1
ACTIVE NOT RECRUITING

NCT05622708

A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission

This study will establish whether prolonged chronic dosing with secukinumab is needed in participants with Non-radiographic axial spondyloarthritis, (nr-axSpA) who have achieved remission. Remission is defined as Ankylosing Spondylitis Disease Activity Score - C-reactive protein (ASDAS-CRP) Inactive Disease (ID) response (ASDAS-CRP \< 1.3). Maintenance of remission on continued secukinumab treatment will be evaluated compared to placebo using a randomized withdrawal design. The primary outcome measure for this study is the proportion of participants remaining flare-free at Week 120.

Gender: All

Ages: 18 Years - 100 Years

Updated: 2026-10-14

21 states

Non-radiographic Axial Spondyloarthritis
TERMINATED

NCT05242588

Evaluate the Preliminary Efficacy, Safety, and PK of Subcutaneous JS005 in Chinese Adult Patients With Active Nr-axSpA

The purpose of this study is to evaluate preliminary efficacy, safety pharmacokinetic (PK) characteristics, pharmacodynamics (PD) haracteristics and immunogenicity of JS005 at different doses in Chinese patients with active non-radiographic axial spondyloarthritis(nr-axSpA). Treatment difference of JS005 150mg,300mg,450mg vs. placebo in Chinese nr-axSpA patients in terms of ASAS 40 response rate at Week 16 as well as safety profile will be provided by the study .

Gender: All

Ages: 18 Years - 65 Years

Updated: 2026-07-21

17 states

Non-radiographic Axial Spondyloarthritis
COMPLETED

NCT04732117

Efficacy and Safety Study of Secukinumab in Chinese Participants With Non-radiographic Axial Spondyloarthritis

The purpose of this study was to evaluate the efficacy, safety, and tolerability of secukinumab in Chinese patients with active non-radiographic axial spondyloarthritis (nr-axSpA).

Gender: All

Ages: 18 Years - 100 Years

Updated: 2026-04-09

15 states

Non-radiographic Axial Spondyloarthritis