Clinical Research Directory

Timing of Oral Hygiene Improvement Relative to Subgingival Instrumentation

This single-centre, randomized split-mouth trial assessed clinical periodontal changes and acute systemic inflammatory responses when supra- and subgingival instrumentation was performed concurrently with oral hygiene instruction or after 90 days of oral hygiene reinforcement. Ten adults with periodontitis participated. One upper and one lower quadrant were randomly allocated to immediate instrumentation, while remaining quadrants received oral hygiene instruction and were instrumented at day 90. Clinical outcomes were evaluated at baseline, day 90 and day 180. High-sensitivity C-reactive protein was sampled before and 24 hours after each instrumentation session.

Mosque-based Oral Health Intervention Using Solomon Design

This quasi-experimental study evaluates a mosque-based oral health education intervention ("Smile With Prophet", SWP) among adult male mosque attendees in Dhaka, Bangladesh, using a Solomon four-group design. A total of 142 participants were enrolled across two mosques (intervention and control). The analytical sample comprises 80 adult male attendees (≥18 years) allocated to four groups: intervention and control, each with pretest-posttest and posttest-only arms (n=20 per group). The SWP intervention consists of oral health education delivered through Friday sermons (khutbas), supported by educational leaflets and provision of miswak. Outcomes are measured at baseline and 3-week follow-up and include oral health knowledge (14-item questionnaire), self-reported tooth brushing practices (15-item questionnaire), and clinical plaque scores (Greene-Vermillion Simplified Oral Hygiene Index, reversed). The primary objective is to evaluate the effect of the intervention on knowledge and plaque scores. The secondary objective is to assess self-reported practice changes.