Clinical Research Directory

Comparing the Extent to Which Apremilast is Made Available in the Body After Administration as an Extended-release or Immediate-release Formulation

The main objective of this study is to compare the relative bioavailability, safety, and tolerability of extended-release and immediate-release apremilast formulations in healthy participants.

A Study of Phenytoin Mucoadhesive Film for Oral Ulcers in Healthy Volunteers

The goal of this clinical trial is to learn if a new 1% Phenytoin mucoadhesive film is safe and works to treat oral ulcers in healthy adult volunteers and patients with oral ulcers. The main questions it aims to answer are the following: Is the 1% Phenytoin film safe and well-tolerated when placed on oral ulcers? Does the film reduce pain and improve ulcer healing compared to a blank film? Researchers will compare participants receiving the 1% Phenytoin mucoadhesive film to those receiving a blank (placebo) film to see if the active film improves healing and reduces pain. Participants will: Have the assigned film placed directly over their oral ulcer once daily for 7 consecutive days. Attend regular clinic visits for check-ups, including blood tests and monitoring of ulcer appearance, body weight, and food intake. Report any pain, discomfort, or changes in their condition to the research team.

Lenalidomide in the Treatment of Mucosal Behçet's Syndrome

The study is to evaluate the efficacy and safety of lenalidomide in the treatment of oral ulcers in adult patients with refractory mucosal Behcet's syndrome.