Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

3 clinical studies listed.

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PMBCL

Tundra lists 3 PMBCL clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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RECRUITING

NCT07249905

Dose Escalation and Dose Expansion Study of MDX2003 in Patients With Different Types of Lymphoma

This study is designed to characterize the safety, tolerability, and anti-tumor activity of MDX2003 in patients with different types of lymphoma

Gender: All

Ages: 18 Years - Any

Updated: 2026-10-28

2 states

Lymphoma
Waldenström Macroglobulinemia (WM)
DLBCL - Diffuse Large B Cell Lymphoma
+5
NOT YET RECRUITING

NCT07638982

Axatilimab + CAR-T for High-Risk Lymphoma

Axatilimab + CAR-T in High-Risk Lymphoma

Gender: All

Ages: 8 Years - Any

Updated: 2026-10-16

1 state

Diffuse Large B Cell Lymphoma (DLBCL)
Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
High-grade B-cell Lymphoma (HGBCL)
+3
NOT YET RECRUITING

NCT07875413

Prizloncabtagene Autoleucel (Prizlon-cel) for the Treatment of Relapsed or Refractory Large B-cell Lymphoma Post FDA Approved CAR T-cell Therapy

This Phase 2, multicenter, open-label study will evaluate the safety and efficacy of a single infusion of Prizloncel, an anti-CD19/CD20 chimeric antigen receptor T cells following lymphodepleting chemotherapy in participants with relapsed/refractory (r/r) diffuse large B-cell lymphoma post FDA approved, commercially available CAR T-cell therapy Approximately 50 participants will undergo leukapheresis, lymphodepletion with fludarabine and cyclophosphamide, and infusion of Prizlon-cel. Participants will be followed for 24 months (approximately 2 years) to evaluate efficacy, safety, CAR T-cell persistence, pharmacokinetics/pharmacodynamics, and biomarkers. Long-term safety follow-up for gene therapy-related events will continue for up to 15 years following CAR T-cell infusion.

Gender: All

Ages: 18 Years - Any

Updated: 2026-10-15

2 states

Large B Cell Lymphoma
LBCL
Diffuse Large B Cell Lymphoma (DLBCL)
+8