Clinical Research Directory

Clinical Effects of Ringers Lactate Versus Sterofundin/ Plasmalyte Solution in Patients With Sepsis

The goal of this clinical trial is to compare the clinical effects of using Ringer's Lactate and Sterofundin/ Plasmalyte as maintenance fluids in adult patients who have undergone abdominal surgery and are septic. The primary outcome will be the change in serum lactate levels. Secondary outcomes will include renal function parameters, qSOFA scores, and the incidence of postoperative complications within the first 72 hours following surgery.

Association Between Preoperative Mediterranean Diet Adherence and Postoperative Bowel Motility

Postoperative bowel motility is an important indicator of recovery after abdominal surgery and may be influenced by preoperative nutritional status. Adherence to the Mediterranean diet has been associated with favorable gastrointestinal function because of its high content of dietary fiber, unsaturated fatty acids, polyphenols, and other bioactive compounds. This prospective observational cohort study aims to investigate the association between preoperative adherence to the Mediterranean diet and postoperative bowel motility in adults undergoing elective abdominal surgery. A total of 110 participants will be assessed for Mediterranean diet adherence using the Mediterranean Diet Adherence Screener (MEDAS). Nutritional status, dietary intake, and perioperative characteristics will be recorded. Postoperative bowel motility outcomes, including time to first bowel sound, first flatus, first defecation, oral intake, and hospital discharge, will be prospectively monitored. The findings are expected to improve understanding of the relationship between preoperative dietary patterns and postoperative gastrointestinal recovery.