Clinical Research Directory

The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty

This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip arthroplasty (THA) or total knee arthroplasty (TKA). A total of 165 adult patients will be randomly allocated into three equal groups: a white noise group, a pink noise group, and a control group (55 participants per group). On the evening prior to surgery (around 10:00 PM), participants in the experimental groups will listen to standardized white noise or pink noise at 45-50 dB for 30 minutes via over-ear, active noise-cancelling headphones. Participants in the control group will receive routine perioperative care without any auditory intervention. Data regarding sleep quality, anxiety levels, pain intensity, nausea, and hemodynamics (blood pressure, heart rate, respiratory rate, and oxygen saturation) will be collected using validated scales and physiological monitoring before and after the intervention as well as in the postoperative period (at 0, 12, and 24 hours).

Adductor Canal Block Versus Parasartorial Compartment Block for Pain Relief and Recovery After Arthroscopic Knee Surgery

The goal of this clinical trial is to compare adductor canal block and parasartorial compartment block for pain relief and functional recovery in adults undergoing elective arthroscopic knee surgery. The main questions it aims to answer are: Which block provides better pain relief at rest and during movement 24 hours after surgery? How do the two blocks compare in opioid use, muscle strength, knee movement, early walking, side effects, and patient satisfaction? Researchers will compare participants who receive an adductor canal block with those who receive a parasartorial compartment block to determine whether one technique provides better pain relief and functional recovery while preserving muscle strength. Participants will: Be randomly assigned to receive either an ultrasound-guided adductor canal block or an ultrasound-guided parasartorial compartment block Have their pain at rest and during knee movement assessed for 48 hours after surgery Have their opioid use, quadriceps muscle strength, knee movement, walking ability, side effects, and satisfaction evaluated after surgery