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Clinical Research Directory

Browse clinical research sites, groups, and studies.

3 clinical studies listed.

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Preoperative Sedation

Tundra lists 3 Preoperative Sedation clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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COMPLETED

NCT04383418

A Trial of Dexmedetomidine Hydrochloride Nasal Spray in Preoperative Sedation of Adults

The study is being conducted to evaluate the efficacy and safety of dexmedetomidine hydrochloride nasal spray for preoperative sedation in adults. To explore the reasonable dosage of dexmedetomidine hydrochloride nasal spray for preoperative sedation.

Gender: All

Ages: 18 Years - 65 Years

Updated: 2026-10-28

Preoperative Sedation
RECRUITING

NCT06853431

Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine Combined With Esketamine for Preoperative Sedation in Pediatric General Anesthesia

For pediatric patients undergoing general anesthesia, poor anesthesia induction compliance often has adverse effects on individual behavior in the early postoperative period. Dexmedetomidine can reduce the cardiovascular responses and postoperative mental adverse reactions caused by esketamine anesthesia induction \[6\]. This study aims to explore the ED50 and ED95 and clinical effects of the combination of dexmedetomidine and esketamine nasal drops for preoperative sedation in children of different ages undergoing general anesthesia, providing a theoretical basis for the combined use of dexmedetomidine and esketamine for preoperative sedation in children undergoing general anesthesia.

Gender: All

Ages: 12 Months - 72 Months

Updated: 2025-12-02

1 state

Preoperative Anxiety
Preoperative Sedation
Children
+5
RECRUITING

NCT07168720

The Study is Being Conducted to Evaluate the Efficacy and Safety of Dexmedetomidine Hydrochloride Microneedles for Preoperative Sedation in Children

The study is being conducted to evaluate the efficacy, safety and the population pharmacokinetic characteristics of Dexmedetomidine Hydrochloride Microneedles for preoperative sedation in children

Gender: All

Ages: 2 Years - 6 Years

Updated: 2025-09-19

1 state

Preoperative Sedation