Clinical Research Directory

Reducing School Dropout and Enhancing Pupils' Sense of Belonging and Participation Through Co-created Music-based Activities

RESONATE is a cluster-randomised crossover trial focusing on reducing school dropout rates and fostering belonging through co-created music-based activites, by combining music therapy (MT), psychology, and social sciences. About 200 participants will be recruited in the area of Bergen, Norway. They will be randomized into the following intervention arms: group music activity followed by usual school schedule or usual school schedule followed by group music activity.

GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH and THRIVE Prospective Cohort Study

This research program includes two coordinated prospective studies (FLOURISH and THRIVE) evaluating the real-world effectiveness of Noom's digital health programs on weight, cardiometabolic biomarkers, physiological health indicators, and program engagement. FLOURISH is a 6-arm prospective cohort study comparing an Education-only control, Noom Weight, standard-dose compounded semaglutide, microdose compounded semaglutide, standard-dose tirzepatide (Noom Plus), and microdose tirzepatide (Noom Plus Microdose). THRIVE is a nested 2-arm prospective study comparing a Proactive Health program to a Noom Free Tier control. Participants complete monthly surveys, remote biomarker collection (Tasso device), connected-scale weigh-ins, and in-app biometric assessments (FaceScan, BodyScan). Microdose and Free Tier arms also use wearable fitness trackers. Primary outcomes are changes in cardiometabolic biomarkers, weight, body composition, and GLP-1 side effect profile. Total N = 2,310; 24-month duration.