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Primary Angiitis of the Central Nervous System (PACNS) in Remission

Tundra lists 1 Primary Angiitis of the Central Nervous System (PACNS) in Remission clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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NOT YET RECRUITING

NCT07902492

Efficacy of Rituximab for Remission Maintenance in Patients With Primary Angiitis of the Central Nervous System: an Open-label, Randomized, Controlled Trial Comparing Systematic Rituximab Infusions and Azathioprine

MAINRIPAC is a multicenter, randomized, open-label controlled clinical trial evaluating the efficacy of rituximab versus azathioprine for maintenance of remission in patients with primary angiitis of the central nervous system (PACNS). Patients are randomized 1:1 to receive either rituximab or azathioprine and are followed for 24 months, with regular clinical and brain MRI assessments to evaluate disease relapse and treatment safety.

Gender: All

Ages: 18 Years - Any

Updated: 2026-10-29

Primary Angiitis of the Central Nervous System (PACNS) in Remission