Clinical Research Directory

A Pilot Study of RISE for Nurse Managers Retreat

The purpose of this study is to determine the feasibility and acceptability of the RISE for Nurse Managers retreat and its impact on occupational and psychological well-being indicators

Trauma-Informed Education and Self-Care for Social Work Students During Field Practicum

This study aims to evaluate the effectiveness of a structured Trauma-Informed Education and Self-Care Intervention in reducing secondary traumatic stress among undergraduate social work students completing their field practicum. During field education, social work students may have direct professional contact with individuals affected by child abuse and neglect, domestic violence, poverty, loss, and other potentially traumatic experiences. Repeated indirect exposure to clients' traumatic experiences may place students at risk for secondary traumatic stress. A total of 80 fourth-year undergraduate social work students will participate in the study. Participants will be allocated to an intervention group (n=40) or a control group (n=40) according to the geographic location of their routine field practicum. Students completing their field practicum in Manisa Province will constitute the intervention group, whereas students completing their field practicum outside Manisa Province, including İzmir and other provinces, will constitute the control group. The intervention group will receive a two-hour Trauma-Informed Education and Self-Care workshop before or at the beginning of field practicum, followed by three structured self-help and peer-sharing group sessions during the practicum period. The control group will continue the routine field practicum process and standard university internship orientation without receiving the study-specific intervention during the study period. Secondary traumatic stress will be assessed repeatedly in both groups throughout the approximately four-month practicum period. Psychological resilience will be assessed at baseline as a supportive participant characteristic. Intervention-related knowledge and skills will also be assessed in the intervention group. The primary hypothesis is that students participating in the Trauma-Informed Education and Self-Care Intervention will demonstrate a more favorable change in secondary traumatic stress over time compared with students in the control group.

The Effect of Web-Based Compassion-Focused Structured Writing Programs on Well-Being in Midwives Working in Delivery Rooms

This randomized controlled trial aims to compare the effects of a web-based compassion-focused writing program and a reflective writing program on psychological well-being, self-compassion, postpartum trauma-related stress symptoms, and post-traumatic growth in midwives working in delivery rooms.

Effect of Mindfulness-Based Self-Compassion Program on Self-Compassion, Secondary Traumatic Stress, and Professional Quality of Life in Midwives and Nurses Working in Obstetrics: A Randomized Controlled Trial

This study aims to examine the effect of a Mindfulness-Based Self-Compassion Program on self-compassion levels, secondary traumatic stress, and professional quality of life in midwives and nurses working in obstetrics. Healthcare professionals in this field are frequently exposed to traumatic experiences such as complicated deliveries, perinatal loss, and obstetric emergencies, which may lead to secondary traumatic stress and reduced professional quality of life over time. This study is designed as a pre-test/post-test randomized controlled trial. A total of 80 participants (40 intervention, 40 control) will be recruited from Gaziantep Cengiz Gökçek Obstetrics and Pediatrics Hospital. The intervention group will receive an 8-week Mindfulness-Based Self-Compassion Program (one session per week, 60-90 minutes each). The control group will receive no intervention. Outcomes will be measured before and after the program using validated scales for self-compassion, secondary traumatic stress, and professional quality of life.

Burnout, Secondary Traumatic Stress and Inflammatory Biomarkers in ICU Healthcare Workers

Healthcare professionals working in intensive care units (ICUs) are frequently exposed to high levels of psychological stress due to critically ill patients, frequent encounters with death, complex clinical decision-making, and prolonged working hours. This environment increases the risk of burnout and secondary traumatic stress, which may not only affect mental well-being but also have measurable physiological consequences. Emerging evidence suggests that chronic psychological stress and burnout may influence immune function through activation of proinflammatory pathways. Elevated levels of inflammatory biomarkers such as C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and neutrophil-to-lymphocyte ratio (NLR) have been associated with stress-related conditions. However, data examining the relationship between burnout, secondary traumatic stress, and inflammatory biomarkers in intensive care healthcare workers remain limited. This cross-sectional observational study aims to investigate the association between burnout and secondary traumatic stress levels, assessed using validated psychometric instruments (Maslach Burnout Inventory and Professional Quality of Life Scale), and inflammatory biomarkers (CRP, IL-6, TNF-α, and NLR) in ICU healthcare workers. Blood samples will be obtained in conjunction with routine annual health screening, and additional serum samples will be collected for biomarker analysis. The study seeks to clarify the psychoneuroimmunological mechanisms underlying occupational stress in critical care settings.

Supportive Care-Based Training and Psychological Outcomes in Midwifery Students

The aim of this study is to comparatively evaluate the effects of trauma-informed supportive care model training in childbirth and universal supportive care model training in childbirth provided to midwifery students on their clinical skill self-efficacy in the delivery room, state anxiety, and secondary traumatic stress levels.