Clinical Research Directory
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3 clinical studies listed.
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Tundra lists 3 Sjogren Syndrome With Keratoconjunctivitis clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT07014059
Autologous Serum Obtained by a Closed-Circuit Collection Device
Autologous serum eye drops (ASED) are an established therapy for ocular surface diseases; however, their preparation can be costly and may not be available due to the need for germ-free conditions. This pilot trial assesses the feasibility of collecting ASED in a closed-circuit system for patients with chronic ocular surface diseases.
Gender: All
Ages: 18 Years - Any
Updated: 2026-10-21
1 state
NCT07671222
Safety and Efficacy of Topical Infliximab in Autoimmune Dry Eye Disease
Sjögren's syndrome is a condition in which the immune system attacks the body's moisture-producing glands. This often causes severe dry eye, leading to discomfort, irritation, blurred vision, and damage to the eye surface. Inflammation plays an important role in this process, and a protein called TNF-alpha is one of the key drivers. This study will test a new eye drop containing infliximab, a medication that blocks TNF-alpha. The goal is to see whether this treatment can safely improve symptoms and signs of severe dry eye in patients with Sjögren's syndrome.
Gender: All
Ages: 18 Years - Any
Updated: 2026-06-26
1 state
NCT07277257
Evaluating a New Therapy for Dry Eye in Patients With Sjögren's Syndrome
This study will evaluate the effect of TRYPTYR in patients with Sjögren's syndrome-related dry eye disease. The goal is to determine whether TRYPTYR can improve symptoms and signs of dry eye in this specific patient population.
Gender: All
Ages: 18 Years - Any
Updated: 2025-12-22
1 state