Clinical Research Directory

Understanding Speech in Background Noise

The goal of this clinical trial is to establish how speech understanding is affected by background noise in people with normal hearing. The main questions it aims to answer are: * Does noise affect speech understanding similarly in all frequency regions? * Does adding noise cause speech understanding to fall away at a similar rate across frequencies? Participants will listen to speech in different frequency regions, with noise added at various levels, and respond with the words that they hear.

Dynamic Neural Mechanisms of Audiovisual Speech Perception

Understanding speech is one of the most important functions of the human brain. We use information from both the auditory modality (the voice the of person we are talking to) and the visual modality (the facial movements of the person we are talking to) to understand speech. We will use intracranial encephalography to study the organization and operation of the brain during audiovisual speech perception.

Auditory Restoration and Outcomes After Gene Therapy and Cochlear Implantation: a PRospective Cohort Analysis (AURORA)

This cohort study aims to explore the trends and differences in multidimensional perceptual levels of patients after cochlear implants or gene therapy, as well as to comprehensively assess the efficacy of gene therapy for congenital deafness, thus providing a reference for making a well-rounded postoperative rehabilitation protocol for gene therapy patients.

Cochlear Implant Recipients: Comprehensive Longitudinal Evaluation

This study aims to assess hearing and speech perception, as well as quality of life, in deaf patients of all ages before and after cochlear implantation, and to explore differences across age groups and treatment subtypes, thereby providing evidence for personalized hearing and speech rehabilitation.

Perceptual Evaluation and Rehabilitation System Development for Congenital Hearing Loss

This study aims to establish a novel multimodal evaluation and precision rehabilitation system for patients with congenital hearing loss who have received hearing aids, cochlear implantation, or emerging gene therapy. The proposed system will integrate age-stratified difficulty levels, combined with a gamified interaction platform or software designed to assess and train three core perceptual domains: auditory speech perception, music perception, and spatial hearing capabilities.

Music-Based Interventions, Aging, Alzheimer's Disease

Using a randomized controlled trial design, the investigators will examine the effects of music engagement through choir training on the hearing, communication, and psychosocial well-being of older adults, particularly those at heightened risk of developing dementia.