Clinical Research Directory

Comparative Effects of Sensorimotor Training and tACS on Upper Limb Function and Cervical Proprioception in Subacute Stroke

Stroke is leading cause of death and disability worldwide, resulting in significant functional limitations and disabilities experienced by stroke survivors. Stroke is an umbrella term that includes disorders such as cerebral infarction, cerebral hemorrhage, and subarachnoid hemorrhage.The aim of this study will be to compare the effects of sensorimotor training and transcranial alternating current stimulation on upper extremity functions, sensorimotor impairment and cervical joint position sense in sub-acute stroke patients. A single blinded randomized clinical trial will be used. Allocation will be concealed by sealed envelope. Non- probability convenient sampling will be done. On the basis of inclusion criteria participants will be randomly allocate in two groups (Group A and Group B) by using computer-generated software. Group A will receive sensorimotor training for 40 mins and TACS for 20 minutes at 2mA current, for 5 days/week for 4 weeks. Group B will receive sensorimotor training for 40 minutes and sham TACS for 20 minutes per session , for 5 days/week for 4 weeks . Measurements will be taken at baseline and at 4th week. Data will be collected using Fugyl meyer assessment scale, cervical joint position error test and revised Nottingham sensory assessment scale. Data analysis will be done by SPSS software version 27. The statistical software IBM SPSS Statistics SPSS 27 will be used for calculations. After assessing the normality by Shapiro-wilk test, if the p value is greater than 0.05 the data will be distributed normally, so parametric test will be applied. If p value is less than 0.05 than non-parametric test will be applied.

Home and Clinic Rehabilitation in Subacute Stroke

The goal of this clinical trial is to learn if adding scheduled home-based rehabilitation to clinic-based rehabilitation improves walking ability and daily activities in people aged 40 to 50 with sub-acute stroke. The main questions it aims to answer are: * Does adding home exercises improve walking ability in people with sub-acute stroke? * Does adding home exercises improve the ability to do daily activities in people with sub-acute stroke? Researchers will compare clinic-based rehabilitation plus home-based rehabilitation to clinic-based rehabilitation alone to see if adding home exercises leads to better recovery after stroke. Participants will: * Attend physical therapy at the hospital 3 days per week for 12 weeks * Do walking practice, balance training, and leg exercises at the clinic * Do home exercises including marching, step-ups, sit-to-stand, and balance exercises on non-clinic days (home exercise group only) * Track home exercises using a weekly logbook * Be tested at the start and after 12 weeks

Combined Effects of Rhythmic Breathing and Balance Training on Balance and Trunk Control in Stroke Patients

The goal of this study is to evaluate the combined effects of rhythmic breathing and balance training on balance, trunk control and postural control in patients with sub-acute stroke. The main questions it aims to answer are: * Will there be a difference in combined effects of rhythmic breathing exercises and balance training on balance and trunk control in patients with stroke? * Will there be no difference in combined effects of rhythmic breathing exercises and balance training on balance and trunk control in patients with stroke? The participants will be evenly divided into two groups, * the experimental group will receive rhythmic breathing exercises along with balance training and conventional physical therapy * the control group will only receive balance training and physical therapy. Both the groups will perform their respective exercises for 60 minutes, 3 days a week for consecutive 8 weeks.

Using Immersive Virtual Reality for the Upper Limb Rehabilitation of Post-stroke Subjects

Stroke produces brain damages that results in sensory, motor, and cognitive impairments which reduce the patient's quality of life and social participation. Upper limb recovery is a complex process whose goal is to allow the patients to gain, in part or completely, independence in daily living activities, for that it represents one of the most important rehabilitation focus. Virtual reality is a fairly recent approach able to simulate concrete movements and functional tasks in a higher dosage compared to other therapies. It seems that the use of VR could improve limb function, however, the amount of this gain is still unclear because of insufficient evidence. This study aims at quantitatively investigating the effectiveness of an HMD immersive virtual reality system on the upper limb functioning in subacute stroke survivors.