Clinical Research Directory

The Effect of Preoperative Oral Care Procedures on Postoperative Thirst Discomfort

Aim: To determine the effect of an oral care procedure using cold distilled water, initiated in the preoperative period, on the level of discomfort associated with thirst in patients undergoing lung resection. Methods: This randomized controlled study was conducted between December 12, 2024, and December 24, 2025 with the participation of a sample of 78 patients who undergoing lung surgery in the Thoracic Surgery Department of a University hospital. Patients who received oral care using cold distilled water at four-hour intervals starting from the time of hospital admission were included in the experimental group.

Effectiveness of Enzyme Spray Intervention on Thirst Relief in Patients With Endotracheal Intubation.

Thirst is a common and distressing symptom among intensive care unit (ICU) patients with endotracheal intubation. Endotracheal intubation, nil per os (NPO) status, oxygen therapy, and medication effects may contribute to oral dryness and thirst. Current approaches such as water or saline sprays may provide only short-term relief, and direct oral water administration may increase the risk of choking or aspiration. Enzyme-based saliva substitutes may help maintain oral moisture by mimicking components of natural saliva, but evidence in ICU populations remains limited. This randomized controlled trial with blinded outcome assessment was conducted in a surgical ICU at a medical center in southern Taiwan. Adults aged ≥18 years with endotracheal intubation expected to exceed 24 hours, a baseline thirst intensity score (NRS-I) ≥3, and the ability to communicate were eligible. A total of 76 participants were randomly assigned in a 1:1 ratio to either an enzyme-based oral spray group or a distilled-water control group. Allocation concealment was achieved using sequentially numbered, opaque, sealed envelopes (SNOSE). Following routine oral care, both interventions were administered using identical opaque spray bottles and standardized procedures. Twelve sprays (approximately 1.56 mL) were applied to four standardized intraoral sites. The co-primary outcomes were thirst intensity (NRS-I) and thirst distress (NRS-D), assessed at baseline and 30, 60, 120, and 240 minutes post-intervention by trained outcome assessors blinded to group allocation. Generalized estimating equations (GEE) were used to evaluate group, time, and group-by-time interaction effects while accounting for correlations among repeated measurements. Predefined safety criteria required discontinuation of the intervention if clinically significant discomfort, choking, respiratory deterioration, or other adverse events occurred.

Effects of Aromatic Solution Applied After Surgery

Today, surgical applications are used to solve many health problems. In order for the surgical intervention to take place, anesthesia applications are often required. Complications such as sore throat, thirst and nausea and vomiting may occur as a result of trauma, local irritation and inflammation of the airway mucosa during anesthesia and tracheal intubation. These complications are in the postoperative period; It may cause delayed oral fluid intake, prolonged dehydration, oral odour, and increased risk of aspiration, hematoma and wound dehiscence due to retching and vomiting, all of which may lead to delayed discharge and increased cost. Aromatherapy, one of the non-pharmacological applications, is frequently applied in reducing postoperative complications and its effectiveness is stated. In this study, the aromatic solution applied after the surgery; It was planned to examine the effect on sore throat, thirst, nausea-vomiting. In addition, the multimodal synergistic effect of lavender oil and ginger oil used in the aromatic solution to be prepared will be utilized. As a result of this study, the effectiveness of the aromatic solution application to be applied to the patients in the postoperative period and the benefits and benefits of the patient's recovery process will be determined. Thus, effective application can be made for the entire postoperative period. It is thought that this study to be conducted will be a guide for future studies on the patient group.

Effect of Cold Water Spray on Swallowing Difficulty, Pain, and Thirst After Thyroid Surgery

Dysphagia and thirst are common in the early period after thyroidectomy and negatively affect patient comfort. This study aims to evaluate the effect of cold water spray on dysphagia, pain during swallowing, and thirst after thyroid surgery. In this randomized controlled trial, patients will be divided into two groups. Patients in the experimental group (n=54) will receive +4 °C cold water sprayed into the mouth once every hour for 6 hours postoperatively, while the control group (n=54) will receive routine care. In both groups, data will be collected hourly for 6 hours.

Comparison of Four Different Methods Used To Relieve Postoperarive Thirst-Related Discomforts

This study was conducted to compare four different methods applied to relieve thirst-related discomfort after surgery. The study is a prospective, randomized controlled, experimental research conducted at Afyonkarahisar Health Sciences University Health Practice and Research Center General Surgery Clinic. The study took place between November 2022 and April 2023. 150 patients divided into control and intervention groups were included. The study aimed to investigate the effects of four different methods of quenching thirst after surgery on patient outcomes. Data collection tools include Patient Introduction and Follow-up Form, Numerical Verbal Scale (0 10) to measure thirst intensity, Safe Protocol for the Management of Early Post-Operative Thirst, Surgical Period Thirst-Related Discomfort Scale (CDSBRÖ), Perianesthesia Comfort Scale (PCS) and satisfaction level. Numerical Verbal Scale (0-10) was used to determine. The focus of the data study between groups was on postoperative thirst management, patient comfort, and satisfaction with different interventions. The significance level of 0.05 was taken as the criterion in interpreting the results.

Administration of a 'Thirst Relieve Kit' Versus Placebo in Patients After Hospital-based Bowel Preparation for Colonoscopy and Assessment of Thirst Intensity

The goal of this study is to evaluate whether a "thirst kit" (lemon popsicle) is effective in reducing thirst intensity in patients undergoing hospital bowel preparation for colonoscopy. The study also aims to assess the impact of the thirst kit on associated symptoms and patient satisfaction. The main questions it aims to answer are: * Does the thirst kit reduce the intensity of thirst after bowel preparation for colonoscopy? * Does the thirst kit reduce symptoms such as dry mouth and dry throat? * How satisfied are patients when using the thirst kit compared to a placebo? Researchers will compare the thirst kit to a placebo to determine its effectiveness in managing thirst during the pre-colonoscopy period. Participants will: * Be randomly assigned to receive either the thirst kit (lemon popsicle) or a placebo * Use the assigned intervention during the hospital preparation period for colonoscopy * Rate thirst intensity, associated symptoms, and satisfaction using numerical scales

Safe Brain Initiative, Operationalizing Precision Anaesthesia

Perioperatively, patients experience an unnecessarily high level of side effects associated with their treatment. These side effects include nausea, severe pain, anxiety, and stress. Moreover, many patients develop postoperative delirium (POD) and neurocognitive dysfunctions, often resulting in long-term cognitive impairment, decreased quality of life, and increased mortality. However, physicians, nurses and their institutions do not receive structured feedback regarding these aspects of each patient's well-being. They may therefore be unable to engage in the essential cause-and-effect learning necessary to evaluate and consecutively reduce such side effects. Effective guidelines conform prevention is the proven key to shielding our patients from adverse Outcomes. The Safe Brain Initiative's high-quality routine data-for-action is a sword and accelerator for moving towards patient-centred, precision care. Thus, establishing a foundation for value-based and patient-centred healthcare development. However, a turnkey real-world solution is challenging to develop and implement and requires substantial resources. As a result, such solutions are usually beyond the scope of a single institution. The SBI platform provides high-quality, real-world data to bridge this gap. It allows monitoring and in-depth analysis of cause and effect in the day-to-day routine of individuals, departments, and institutions. The SBI's approach is continuously improved and updated. An organization called the SBI Global Society oversees the quality and precision of science through experts in the field. At SBI Hospitals and Flagship centres, Masterclasses are conducted and can be attended alongside clinical immersions. SBI Solutions manages, develops, and provides technical and service support for the Safe Brain Initiative. Its service guarantees the professional and GDPR conform management of data handling and storage as well as the user-friendly functionality of the SBI-Dashboard solutions.

The Effect of Intervention About Dry Mouth and Thirst in Patients With Endotracheal Tube

This is an experimental study aimed at exploring the effectiveness of using 4°C frozen gauze with normal saline for relieving dry mouth and thirst in patients with endotracheal tubes.