Clinical Research Directory

Clinical Time and Temporal Dynamics Study (CLIN-TIME)

TH-CLINICAL-TIME is a prospective, longitudinal observational study evaluating how changes in clinical measurements over time may help researchers better understand patient health trajectories and clinically meaningful outcomes. The study will examine patterns such as changes from an individual's baseline, rate of change, persistence of abnormalities, variability, recurrence, and recovery following clinical events. Data may include routinely collected clinical measurements, physiologic observations, laboratory results, cardiac measurements, imaging-derived measurements, patient-reported information, and remote or digital health data when available and permitted by the study protocol. The study will investigate whether these temporal patterns provide additional information beyond individual measurements taken at a single point in time. The planned study horizon extends from 2026 through 2076, while individual participant follow-up will occur according to the approved study schedule, consent, and applicable requirements.

Assessing the Role of Pharmaceutical Technical Assistents in Hospital Wards: Measuring Efficiency and Medication Safety

The goal of this interventional study is to evaluate the impact of implementing pharmaceutical technical assistants (PTAs) to support the medication process on hospital wards on operational efficiency and medication safety among nurses and pharmaceutical technicial assistants. The main questions it aims to answer are: * What is the effect of PTAs on the time spent by (night) nurses on medication dispensation? * How does their involvement influence unplanned interactions between nursing staff and the pharmacy? * What is the impact of PTAs on the safety of medication processes, including missed or delayed doses, accuracy of dispensed medication, and reported medication errors? Researchers will compare periods with and without the involvement of PTAs in the medication management process on the hospital ward to assess differences in: * Time spent on medication dispensation. * Frequency of unplanned interactions between hospital wards and the pharmacy. * Rates of missed or delayed medication doses. * Accuracy of dispensed medication compared to prescriptions. * Reported medication errors. During the observed medication dispensation processes, involved nurses and PTAs will: * Be observed while preparing medications to measure time and interruptions. * Provide data on medication errors and delays through digital systems and reports. * Complete a demographic questionnaire about their professional background. This study involves both intervention and control periods, allowing researchers to measure the specific effects of PTAs' involvement in medication processes.