Clinical Research Directory

Effects of Online and App-Based Prenatal Yoga on Birth Outcomes

This randomized controlled trial evaluated the effects of a midwife-led digital prenatal yoga intervention via the MIDWIFEYOGA mobile application on birth and neonatal outcomes among 74 primiparous women. The intervention group practiced yoga twice weekly for 45 minutes using the application, alongside one weekly online session. Results showed that the intervention group experienced significantly lower rates of labor induction and analgesia use, shorter labor duration, reduced pain, and higher birth satisfaction. Additionally, neonatal birth weights, Apgar scores, and early breastfeeding assessment scores were significantly improved. A midwife-led digital prenatal yoga program provides an accessible, non-pharmacological approach to reducing obstetric interventions, enhancing birth satisfaction, and supporting positive early neonatal outcomes.

Onlıne Yoga Compared to Face-To-Face Yoga on Dıaphragm Thıckness, Body Balance and Psychosocıal Status

The aim of this controlled study was to compare the effects of a six-week online yoga program and a six-week face-to-face yoga program on diaphragm function, body balance, and psychosocial outcomes in young women. The main questions were: * Does online yoga have similar effects to face-to-face yoga on diaphragm outcomes? * Does online yoga have similar effects to face-to-face yoga on body balance? * Does online yoga have similar effects to face-to-face yoga on psychosocial outcomes, including anxiety and social media addiction? This was a non-randomized controlled study in which the online and face-to-face yoga interventions were conducted during different recruitment periods because of the COVID-19 pandemic. Participants in the online yoga group completed a six-week online yoga program during the period when face-to-face group exercise was restricted. After pandemic-related restrictions were lifted, participants recruited in a subsequent period completed the six-week face-to-face yoga program. Thus, allocation to the online and face-to-face intervention groups was determined by the recruitment period rather than by random assignment. Participants underwent assessments before and after the six-week study period, including diaphragm ultrasound imaging, balance testing, and self-reported psychosocial measures. A control group that did not participate in either exercise intervention was also assessed twice, six weeks apart. Outcomes were compared across the online yoga, face-to-face yoga, and control groups.

The Effects of Innatal Yoga Practices on Pain, Comfort, and Satisfaction in Primiparous Women

The aim of this study is to examine the effects of prenatal yoga practices on labor pain, comfort level during labor, and overall birth satisfaction in primiparous pregnant women in Turkey. This study, which will be conducted using a randomized controlled trial design, aims to measure both the physical contribution of prenatal yoga practice to the birthing process and its effects on psychological well-being and satisfaction, thereby providing evidence-based recommendations to improve the quality of childbirth services.

Fascial Yoga in Menopausal Women

Aim: The aim of this study is to evaluate the effects of a structured fascial yoga-based behavioral intervention on perceived stress, cognitive control, and cognitive flexibility in menopausal women. The study aims to determine whether a non-pharmacological and non-invasive behavioral intervention can support psychological and cognitive functioning and reduce perceived stress in menopausal women. Design: This study is designed as a randomized controlled, pretest-posttest experimental study with a post-intervention follow-up assessment. Eligible participants will be randomly assigned to either the intervention group or the control group receiving usual care. Outcomes will be assessed at baseline, immediately after the intervention, and at follow-up to evaluate both the immediate and sustained effects of the intervention. Method: A total of 60 menopausal women aged 45-65 years will be recruited from the menopause outpatient clinic and randomly assigned to either the intervention group or the control group. The intervention group will participate in a 12-week online fascial yoga program consisting of two 60-minute sessions per week. In this study, fascial yoga is defined as a fascia-focused, non-pharmacological, and non-invasive behavioral intervention that includes myofascial release techniques, breath regulation, body awareness, and basic yoga practices to support stress regulation and cognitive functioning. The program will include myofascial release techniques, basic yoga postures suitable for all physical fitness levels, and structured breathing exercises. All sessions will be conducted online in a group format, and no audio or video recordings will be taken. The control group will continue to receive routine outpatient care during the study period. After completion of the follow-up assessments, the fascial yoga program will be offered to participants in the control group upon request. Data will be collected at three time points: at baseline before the intervention, immediately after completion of the 12-week intervention, and at the follow-up assessment 8 weeks after the intervention. Perceived stress, cognitive control, and cognitive flexibility will be assessed using validated self-report questionnaires. Hypotheses: H1: Menopausal women participating in the fascial yoga intervention will show a significant reduction in perceived stress levels compared with the control group at post-intervention and follow-up assessments. H2: Menopausal women participating in the fascial yoga intervention will show a significant improvement in cognitive control and cognitive flexibility compared with the control group at post-intervention and follow-up assessments.

Yoga Asana Chandra Harmoni on Psychological Well-being and Learning Readiness Among Medical Students

The goal of this trial is to learn if the Yoga Asana Chandra Harmoni intervention can improve psychological well-being and learning readiness in medical students. The main questions it aims to answer are: Does Yoga Asana Chandra Harmoni improve psychological well-being (specifically, reduce stress, anxiety, and depression) in medical students? Does Yoga Asana Chandra Harmoni enhance self-directed learning readiness in medical students? Researchers will compare a group receiving the Yoga Asana Chandra Harmoni intervention to a control group to see if the intervention leads to significant improvements in psychological well-being and self-directed learning readiness. Participants will: Complete baseline questionnaires assessing psychological well-being, sleep quality, self-directed learning readiness, and self-efficacy. Participate in 3 weekly Yoga Asana Chandra Harmoni sessions for 4 weeks (intervention group). Continue with their usual activities (control group). Complete follow-up questionnaires at post-test (end of week 4) and at a 2-week follow-up to assess changes in the outcome measures. Engage in additional online audio guided practices 5 times/week for 20-30 minutes, including breathing exercises (weeks 1-2) and body scans (weeks 3-4) (intervention group).

Examining the Effectiveness of Asynchronous Versus Synchronous Yoga for Veterans With Chronic Pain

The goal of this clinical trial is to see if pre-recorded yoga videos are as helpful for chronic pain as online yoga sessions taught in real time. The main questions it aims to answer are: Are pre-recorded yoga videos an acceptable and practical tool and could they be used more broadly? Are pre-recorded yoga videos no worse than online yoga sessions taught in real time for managing chronic pain? Researchers will compare changes in chronic pain, mental health, and quality of life outcomes for participants who attend pre-recorded yoga videos versus online yoga sessions taught in real time. Over the course of 4 months, participants will: Attend a 5-session virtual yoga course. Continue virtual yoga practice for 12-weeks on their own or in a VA online class. Complete 3 online assessments and a brief exit interview.

Examining Yoga's Effects on Smoking

The primary aim of this research study is to examine the effects of an 8-week yoga program on aspects related to nicotine dependence, stress, and coping during a smoking quit attempt. Guided by initial studies reporting on the effects of yoga on putative mediators of smoking relapse (i.e., cortisol, distress intolerance, withdrawal symptoms), the proposed experiment examines the effects of an 8-week yoga practice on nicotine withdrawal intensity by way of aiding withdrawal characteristics predictive of smoking relapse. The long-term objectives of the proposed line of research are to: (1) inform theoretical models of nicotine withdrawal, (2) guide the development of effective alternative interventions for smokers susceptible to relapse during the critical withdrawal period (i.e., smokers low in distress tolerance), and (3) to help guide behavioral strategies for treating substance addictions broadly.

Effect of Yoga Program on Quality of Life in Women With Breast Cancer Receiving Endocrine Therapy

The goal of this randomized controlled trial is to evaluate the effect of a yoga program on improving the quality of life, reducing joint pain, and alleviating vasomotor symptoms (night sweats, hot flashes) in women with breast cancer undergoing endocrine therapy. The main questions it aims to answer are: Does the yoga program significantly improve the quality of life in women with breast cancer undergoing endocrine therapy? Is the yoga program effective in reducing joint pain in women with breast cancer? Does the yoga program reduce the severity of night sweats and hot flashes in women with breast cancer? Researchers will compare the intervention group, which will receive the yoga program, to the control group, which will continue with their physician-recommended routine exercise, to see if there is a difference in these outcomes. Participants will: Participants will consist of women with breast cancer undergoing endocrine therapy, with 34 in the yoga (intervention) group and 34 in the control group. Complete the;Patient Assessment Form; and the Functional Assessment of Cancer Therapy - Endocrine Symptoms (FACT-ES) scale. The intervention group will participate in a 70-minute yoga program, delivered online via a digital platform, four days a week for six weeks, led by an instructor. The control group will not receive any intervention and will continue with their physician-recommended routine exercise.

Effects of an Online Yoga Program on Exercise Capacity and Quality of Life in Bronchiectasis Patients

Bronchiectasis is a chronic lung disease characterized by persistent cough, sputum production, shortness of breath, and recurrent infections, which can reduce physical capacity and quality of life. Non-pharmacological interventions, such as exercise-based approaches, are increasingly used to support symptom management in these patients. This study aimed to evaluate the effects of an eight-week online yoga program on exercise capacity, dyspnea severity, respiratory function, and quality of life in adults with non-cystic fibrosis bronchiectasis. A total of 70 participants were randomly assigned to either a yoga intervention group or a control group. The yoga group participated in supervised online sessions three times per week, including breathing exercises, postures, and relaxation techniques, while the control group received usual care without additional intervention. Outcomes were assessed at baseline and after eight weeks using pulmonary function tests, the six-minute walk test (6MWT), the Modified Medical Research Council (mMRC) Dyspnea Scale, and the St. George's Respiratory Questionnaire (SGRQ). The study investigated whether yoga could provide a safe and effective complementary approach to improve symptoms and functional capacity in individuals with bronchiectasis.

Effects of a Structured Physical Activity Program on Balance and Functional Performance in Children With Down Syndrome

Children with Down syndrome commonly exhibit hypotonia, impaired balance, and reduced functional mobility. This study aimed to evaluate the effects of a structured yoga-based physical activity program on balance and functional performance in children with Down syndrome. Fifteen children aged 7-12 years participated in a 12-week intervention program consisting of adaptive yoga exercises, breathing techniques, and relaxation practices. Outcome measures included balance assessment using a sensor-based digital system and functional performance tests. The findings are expected to provide evidence on the effectiveness of structured physical activity interventions in improving motor performance in children with Down syndrome.

The Effect of a Four-Week Hatha Yoga Intervention to Improve Quality of Life, Anxiety, and Depressive Symptoms in Individuals Undergoing Assisted Reproductive Technology (ART) Treatment

The goal of this clinical trial is to learn if a four-week yoga program works to improve quality of life in people undergoing IVF (In Vitro Fertilization). It will also learn if a four-week yoga program decreases anxiety and depression symptoms in people undergoing IVF. The main questions it aims to answer are: * Does a four-week yoga program effect quality of life, anxiety, and depression symptoms in people undergoing IVF? * Do the effects vary by individual characteristics of the people in the study? Researchers will compare the yoga intervention group to routine care as usual. Participants will: * Participate in a weekly virtual yoga class for four weeks (total of four yoga classes), or follow routine care as usual while undergoing IVF. * Take three online surveys every 4 weeks. * Be involved in the study for 8 weeks.

Yoga in Women With Surgical Menopause After Gynecological Cancer

This randomized controlled trial investigates the effects of yoga on quality of life, sleep quality, and spiritual well-being in women who have entered surgical menopause after gynecological cancer surgery. Yoga is expected to be a supportive intervention for symptom management and to improve overall well-being in this patient population.

Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness

The study aims to evaluate the effects of a 9-month intervention combining yoga-based mindfulness techniques, cognitive training, and nutritional counseling on cognitive function, plasma markers of neurodegeneration (tau protein), physical fitness, and metabolism in older adults at increased risk of developing Alzheimer's disease.

Effect of Yoga Training on Nausea and Pain

This study was planned to determine the effect of yoga training on reducing nausea and pain symptoms in young women with primary dysmenorrhea. As a result of this study, evaluating the extent to which women with dysmenorrhea experience pain and nausea and the extent to which yoga has a positive effect on these symptoms may shed light on women experiencing these symptoms and developments in the literature, and may increase the use of non-pharmacological approaches. The results of the study will contribute to the literature on dysmenorrhea, one of the important gynecological problems in women. In addition, although there are many results in the literature on the effectiveness of yoga in the management of nausea symptoms with cancer patients, there are not many studies on nausea on dysmenorrhea. In this respect, it will provide important evidence to the literature.

Comparison of the Effects of Yoga and Conventional Physiotherapy Programs in Sarcoidosis

Sarcoidosis is a multisystem disease, characterized by the formation of immune granulomas with various clinical symptoms depending on the involved organs, which can involve many organs and systems associated with emotional and physical consequences that affect the quality of life, whose cause is unknown, but usually affects the respiratory system, and occurs mostly in young and middle-aged adults. Lung involvement, seen in 95% of patients, causes limitation of lung capacity and decrease in inspiratory muscle strength, which are important factors that lead to an increase in dyspnea and a decrease in walking distance. In addition to respiratory muscle weakness, skeletal muscle dysfunction is also frequently observed. The most common symptoms in sarcoidosis are dyspnea and fatigue. When the current literature is examined, it can be seen that studies on non-pharmacological treatment methods in Sarcoidosis are quite limited. Although relatively common in Chronic Obstructive Pulmonary Disease (COPD), various studies conducted in patients with Bronchiectasis, Pulmonary Arterial Hypertension and Asthma have shown that yoga results in a decrease in dyspnea and fatigue, and an increase in pulmonary functions and exercise capacity. On the other hand, no study has been found on yogic techniques in Sarcoidosis. Aim of this study is to investigate the effects of yogic techniques and conventional physiotherapy program on pulmonary functions, body oxygen level test (BOLT), exercise capacity (6MWT), anxiety, depression, fatigue, dyspnea perception, sleep quality, and quality of life in sarcoidosis cases at different stages. In these patients known to have multisystem involvement, holistic approaches gain importance due to the nature of the disease.