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Management of Breast Fibroadenoma: Comparing Observation, Microwave Ablation, and Surgical Excision
Sponsor: Sohag University
Summary
The purpose of this study is to evaluate and compare three different management strategies for benign breast fibroadenoma: conservative management with clinical and radiological follow-up (observation), ultrasound-guided percutaneous microwave ablation (MWA), and conventional open surgical excision. Fibroadenoma is the most common benign solid breast tumor in young women. While conventional surgical excision provides complete tissue removal, it may result in visible surgical scars, breast volume loss, and contour deformity. Minimally invasive thermal techniques such as microwave ablation offer potential advantages in tissue preservation and cosmetic satisfaction under local anesthesia. This study aims to assess and compare the therapeutic success, safety, postoperative pain, recovery period, complication rates, and cosmetic outcomes among female patients undergoing these three approaches at Sohag University Hospital.
Official title: Management of Breast Fibroadenoma; Multidisciplinary Approach: A Comparative Interventional Study Evaluating Conservative Management, Ultrasound-Guided Microwave Ablation, and Conventional Surgical Excision
Key Details
Gender
FEMALE
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-11
Completion Date
2027-07
Last Updated
2026-10-22
Healthy Volunteers
No
Interventions
Ultrasound-guided percutaneous microwave ablation
Percutaneous thermal ablation of the fibroadenoma was performed under continuous ultrasound guidance using a cooled-shaft microwave antenna following hydrodissection with 2% lidocaine and saline to protect the surrounding skin, nipple-areola complex, and pectoralis fascia.
Conventional open surgical excision
Standard open surgical excision of the breast fibroadenoma performed en bloc with a minimal margin of normal breast tissue via periareolar or skin-crease incisions, followed by meticulous hemostasis and layered absorbable subcuticular wound closure.
Locations (1)
Sohag University Hospital
Sohag, Egypt