Clinical Research Directory

Inclusion Criteria: * Between 18 and 75 years of age * Body mass index (BMI) between 18 and 35 kg/m2 * Estimated GFR ≥15 and \<60 mL/min/1.73 m2 * CKD for at least 3 months * Not currently receiving dialysis and not expected to start dialysis within 3 months of screening. * Hemoglobin ≥9.0 g/dL and ≤11.5 g/dL * Transferrin saturation (TSAT) ≤20% * Not folate or vitamin B12 deficient * ALT and AST ≤1.5 x ULN and TBL ≤1.5 x ULN Exclusion Criteria: * Anemia due to a cause other than CKD, presence of active bleeding, or recent significant blood loss * Any hemoglobinopathy, bone marrow pathology or hematological malignancy, including, but not limited to sickle cell disease, thalassemia, myelodysplastic syndrome, bone marrow fibrosis, red cell aplasia * Known history of hemochromatosis or other iron-overload disorder, or ferritin \>700 ng/mL * RBC transfusion, intravenous iron, or ESA use within 12 weeks prior to screening * Receiving an SGLT2 inhibitor on a dose that has not been stable for at least 12 weeks prior to screening. * Pregnant or breastfeeding. * Is unable or unwilling to comply with protocol-specified sun protection and contraception requirements. * Has any disorder that would interfere with the absorption, distribution, metabolism, or excretion of drugs. * Has a concurrent disease or condition or physical, psychological, mental, and/or social reason that, in the opinion of the Investigator, would make the participant unsuitable for participation in the clinical study.