Clinical Research Directory

St. John's Wort Oil Versus Chlorhexidine Mouthwash for Gingival Problems After Rapid Maxillary Expansion

The goal of this clinical trial was to learn whether St. John's wort (Hypericum perforatum) oil helps gum healing in children and adolescents aged 11 to 16 years after treatment with a rapid maxillary expansion appliance. This appliance widens the upper jaw, but it covers a large part of the palate and makes cleaning difficult, which can cause gum redness, bleeding, swelling and pain after the appliance is removed. The main questions it aimed to answer were: Does St. John's wort oil improve gum health after the appliance is removed? Does it reduce pain in the days after appliance removal? Researchers compared St. John's wort oil with chlorhexidine mouthwash, a commonly used oral antiseptic, and with a control group that used no antiseptic product. Participants: Were randomly assigned to one of three groups after removal of the expansion appliance Used St. John's wort oil as a mouthrinse or chlorhexidine three times a day for 7 days, or used no product (control group) Had their gums examined before the appliance was placed, when it was removed, and 7, 14 and 30 days later Recorded their pain level on a 0-10 scale on several days after appliance removal

Correlation Between Nasal Septal Deviation and Transverse Maxillary Deficiency on CT Scans

The maxillary bones and the nasal septum are interconnected structures. The nasal septum acts as a growth center that facilitates normal maxillofacial growth and development. The objective of this study is to evaluate the presence or absence of septal deviation, as well as its degree of severity, within two adult population groups with or without maxillary transverse deficiency. This is a retrospective CT scan study. While several studies have been conducted in this field, our study is original in its approach to: maxillary transverse deficiency as a measure of the transverse dimension of the maxilla, the use of CT scans as the radiological medium for evaluating the primary endpoint, and finally, the specific method used to measure septal deviation. If a correlation exists between the two, it would be interesting to investigate whether maxillary transverse deficiency leads to septal deviation, or if septal deviation contributes to maxillary deficiency through nasal obstruction. This could highlight the importance of early management of both maxillary transverse deficiency and nasal obstruction. In adult patients, it could support the idea of performing a single combined procedure involving maxillary expansion and septoplasty, which would reduce comorbidities and risks; ultimately representing a true benefit for the patient.