Clinical Research Directory

Ozonated Olive Oil for Mini-Screw Complications in Molar Intrusion

The goal of this clinical trial was to learn whether ozonated olive oil can reduce complications around orthodontic mini-screws in patients with anterior open bite who receive maxillary molar intrusion as part of fixed orthodontic treatment. The study also compared ozonated olive oil with chlorhexidine, the antiseptic most commonly used for this purpose. The main questions it aimed to answer were: * Does ozonated olive oil reduce bleeding, plaque accumulation and mobility around mini-screws compared with chlorhexidine? * Does ozonated olive oil affect pocket depth, bleeding, plaque and mobility of the teeth next to the mini-screws? * Is pain after mini-screw placement different between the two products? Each participant received four mini-screws (two buccal, two palatal) in the upper jaw. One side of the mouth was treated with ozonated olive oil spray and the other side with chlorhexidine spray (split-mouth design), and the side for each product was chosen randomly. Participants: * Applied 10 sprays per day of each assigned product to its side for 7 days after mini-screw placement * Attended measurements before treatment, on the day of placement, and on days 7, 14 and 21 * Rated their pain on a visual analog scale at set time points after placement